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As we gear up for the thrilling matchup on September 27, 2025, between the UConn Huskies and the Buffalo Bulls, anticipation is reaching a fever pitch. This NCAAF showdown at UB Stadium in Buffalo, NY, promises to be a highlight of Saturday football. The Huskies, fresh off a solid season, are looking to capitalize on their momentum. Meanwhile, the Bulls are eager to defend their home turf and turn the tables on their rivals.
Our picks for this encounter favor the Huskies, with a predicted scoreline of 28-21 in their favor. Historically, the Huskies have a strong hit rate in American Total markets, boasting a 60% success rate in their last 10 games. This makes betting on the Huskies a savvy choice. Moreover, our prediction model shows a high EV for the Huskies' moneyline, making them a solid bet.
Catch all the action live on ESPN+ and get ready for a game full of excitement and strategic play. Whether you're placing bets or just enjoying the game, this is one event you won't want to miss. For more insights and expert picks, don't forget to check out our NCAAF picks page.
Ready to elevate your betting game? Explore OddsTrader Turbo for advanced analytics and insights.
East Carolina 2-252% -4½ -114FanDuel | |||||||
![]() Virginia 3-184% +7 -109BetRivers | |||||||
![]() Arizona State 3-160% -2½ -110Caesars | |||||||
![]() Oregon State 0-480% +13½ -110Caesars | |||||||
![]() Ohio 2-220% -10 -110Caesars | |||||||
![]() Arkansas 2-263% +5½ -115BetMGM | |||||||
![]() Pittsburgh 2-174% +5 -114SugarHouse | |||||||
Syracuse 3-123% +5½ -108FanDuel | |||||||
![]() Wake Forest 2-167% +14 -110Caesars | |||||||
Minnesota 2-158% -5½ -110FanDuel | |||||||
![]() Kansas 3-114% -5½ -110Caesars | |||||||
![]() North Texas 4-022% -12 -113SugarHouse | |||||||
![]() Kansas State 1-379% -5½ -115BetMGM | |||||||
#23Illinois 3-180% +6½ +100BetMGM | |||||||
![]() #18Vanderbilt 4-017% -22½ -110Caesars | |||||||
Central Michigan 2-257% -5½ -110Caesars | |||||||
![]() James Madison 2-120% -16½ -120FanDuel | |||||||
![]() Louisiana-Monroe 2-1100% -2½ -105Caesars | |||||||
![]() Toledo 2-20% -20½ -122FanDuel | |||||||
West Virginia 2-2100% +10½ -105BetMGM | |||||||
![]() Northern Illinois 1-282% +3 -110SugarHouse | |||||||
![]() Boston College 1-250% -6½ -108FanDuel | |||||||
Buffalo 2-2100% +3 -110Caesars | |||||||
Iowa 3-172% +8½ -118FanDuel | |||||||
![]() Northwestern 1-260% -6½ -115Caesars | |||||||
Navy 3-067% -14½ -108BetRivers | |||||||
Oklahoma State 1-267% +20½ -108BetRivers | |||||||
![]() #13Ole Miss 4-033% -1½ -110Caesars | |||||||
#9Texas A&M 3-044% -5½ -120SugarHouse | |||||||
![]() Washington 3-087% +9½ -113BetRivers | |||||||
Miami (OH) 0-3- -20½ -110FanDuel | |||||||
Air Force 1-20% -5½ -115BetMGM | |||||||
![]() New Mexico 2-10% -13½ -115FanDuel | |||||||
![]() Tulsa 2-250% +14½ -106FanDuel | |||||||
![]() Mississippi State 4-089% +8½ -113BetRivers | |||||||
![]() Old Dominion 2-133% -16 -110Caesars | |||||||
![]() Kennesaw State 2-20% -7½ -108BetRivers | |||||||
![]() Western Michigan 1-3- -7½ -110FanDuel | |||||||
![]() Florida Atlantic 1-294% +13½ -105BetMGM | |||||||
![]() North Carolina State 3-143% -10½ -110Caesars | |||||||
Southern Miss 2-2- -3½ -113BetRivers | |||||||
![]() #14Iowa State 4-015% -5½ -110Caesars | |||||||
![]() Missouri State 2-2100% +5½ -112BetRivers | |||||||
![]() Boise State 2-167% -16 -113BetRivers | |||||||
Stanford 1-333% -2 -113BetRivers | |||||||
![]() #20Missouri 4-0100% -44½ -110Caesars | |||||||
![]() Colorado State 1-20% -4½ -110Caesars | |||||||
![]() #3Penn State 3-085% -3 -120Caesars | |||||||
![]() #5Georgia 3-037% -2½ -122FanDuel | |||||||
![]() South Carolina 2-233% -6½ -110Caesars | |||||||
![]() Louisiana 1-3100% -1½ -110Caesars | |||||||
![]() UTEP 1-3100% +4 -110Caesars | |||||||
![]() Colorado 2-260% +6½ -105Caesars |
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