SMU Mustangs vs Clemson Tigers Odds

Get ready for an exhilarating clash as the SMU Mustangs take on the Clemson Tigers on October 18, 2025, at Memorial Stadium in Clemson, SC. This NCAAF showdown promises to deliver electrifying Saturday football action. The Mustangs are eager to prove themselves on the road against the formidable Tigers, making this a must-watch game for college football enthusiasts. The game kicks off at 3:30 PM and will be broadcasted on the ACC Network. With the odds in favor of the Tigers, bettors can expect a thrilling contest.

Current odds show the Tigers as the favorites, but the Mustangs have been known to defy expectations. The opening odds had the Tigers at -6½ -110, which has now shifted to -7 -115, indicating a growing confidence in their performance. The over/under is set at o55½ -110, suggesting a high-scoring affair. For those looking to place a wager, the current best odds for the Tigers are -7 -115 at SugarHouse. Meanwhile, the Mustangs are available at +7 -110, offering potential for those backing the underdogs.

Betting enthusiasts can enhance their strategy with an OddsTrader Turbo subscription. For more detailed insights and to compare odds, visit our NCAAF odds page. Whether you're a seasoned bettor or new to the game, these insights can help you make informed decisions and maximize your betting experience.