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As we anticipate the clash on September 20, 2025, between the Syracuse Orange and the Clemson Tigers at Memorial Stadium in Clemson, SC, fans and bettors alike are preparing for an exciting showdown. This NCAAF matchup is set to be a thrilling encounter, broadcasted on ESPN. Syracuse will be looking to leverage their offensive prowess, having averaged 379.3 passing yards per game, led by their star quarterback, while Clemson's defense, allowing only 227.3 passing yards, aims to counteract this threat.
Clemson's offense, although not as high-scoring, has shown resilience with a 211-yard average in passing. Syracuse's defense, which has allowed 274 passing yards on average, will need to tighten up to prevent Clemson from exploiting this gap. The spread is currently set at 17 points in favor of Clemson, according to Caesars, with the total points over/under set at 55.5. This spread suggests a strong confidence in Clemson's ability to cover, given their superior defensive stats.
Betting trends highlight Clemson's current 0-3 ATS record, suggesting a potential opportunity for bettors to capitalize on Syracuse's 1-1-1 ATS standing. With both teams showcasing dynamic play styles, this game promises not only an exciting watch but also a lucrative betting opportunity. Ready to bet smarter? Start your OddsTrader Turbo subscription now or check our NCAAF standings page for more insights.
Oklahoma State 1-130% -10½ -114BetRivers | |||||||
Rutgers 3-055% +2½ -107BetRivers | |||||||
Army 1-177% +2 -110Bet365 | |||||||
TCU 2-034% -7 -110Caesars | |||||||
Miami (OH) 0-278% +2½ -106BetRivers | |||||||
Louisville 2-046% -25½ -110BetMGM | |||||||
![]() Clemson 1-275% -16½ -110Caesars | |||||||
![]() Wisconsin 2-147% -9 -113BetRivers | |||||||
![]() #16Utah 3-057% -3 -115Caesars | |||||||
![]() Memphis 3-067% +7½ -106FanDuel | |||||||
![]() South Florida 2-1- -27½ -118FanDuel | |||||||
Virginia Tech 0-3- -35½ -110Bet365 | |||||||
#15Tennessee 2-113% -39 -110Bet365 | |||||||
Central Michigan 1-2- -28½ -110Bet365 | |||||||
![]() #6Oregon 3-021% -34½ -114Caesars | |||||||
Eastern Michigan 0-352% +2½ -110Caesars | |||||||
UCF 2-032% -6½ -122FanDuel | |||||||
#7Florida State 2-027% -45 -109BetRivers | |||||||
![]() Western Michigan 0-362% +15 -114BetRivers | |||||||
Buffalo 2-129% -6 -114SugarHouse | |||||||
![]() #11Oklahoma 3-020% -6½ -122FanDuel | |||||||
![]() #13Ole Miss 3-08% -12½ -110Caesars | |||||||
![]() Connecticut 1-271% -21 -110Caesars | |||||||
Nebraska 3-050% +2½ -110BetMGM | |||||||
#24Notre Dame 0-260% -25 -110Caesars | |||||||
![]() Liberty 1-256% +8½ -110BetMGM | |||||||
![]() Ohio 1-2- -25½ -105FanDuel | |||||||
![]() Duke 1-267% -2½ -115Bet365 | |||||||
![]() Mississippi State 3-022% -21½ -110BetMGM | |||||||
![]() #18Georgia Tech 3-021% -22½ -115FanDuel | |||||||
![]() San Jose State 0-2- -14½ -106FanDuel | |||||||
![]() Kansas 2-146% -12½ -110Bet365 | |||||||
![]() Kennesaw State 1-282% +5½ -110FanDuel | |||||||
![]() Florida International 2-121% -4½ -110BetMGM | |||||||
![]() Akron 0-3- -7½ -110Bet365 | |||||||
![]() South Alabama 1-215% -14 -120SugarHouse | |||||||
![]() #23Missouri 3-019% -9½ -110Caesars | |||||||
![]() Western Kentucky 2-17% -9½ -110Caesars | |||||||
Air Force 1-174% +11½ -110BetMGM | |||||||
![]() Middle Tennessee 1-243% +3 -120SugarHouse | |||||||
![]() Jacksonville State 1-2- -35½ -110Bet365 | |||||||
![]() Georgia Southern 1-2- -23½ -110Bet365 | |||||||
![]() Missouri State 1-2- -13½ -110Bet365 | |||||||
East Carolina 2-177% +6½ -110Caesars | |||||||
![]() #4Miami (FL) 3-015% -8 -113BetRivers | |||||||
![]() #19Indiana 3-064% -6 -110BetMGM | |||||||
Baylor 2-118% -2 -114BetRivers | |||||||
![]() Virginia 2-130% -15½ -110BetMGM | |||||||
![]() Louisiana Tech 2-135% -3½ +100Caesars | |||||||
![]() Washington State 2-159% +20 -115SugarHouse | |||||||
![]() #20Vanderbilt 3-037% -27½ -115BetMGM | |||||||
#3LSU 3-0- -39½ -110Bet365 | |||||||
![]() #8Texas 2-143% -39½ -110Bet365 | |||||||
![]() Utah State 2-1- -23½ -110Bet365 | |||||||
Texas State 2-1- -28½ -105FanDuel | |||||||
![]() UTEP 1-218% -6½ -110Bet365 | |||||||
![]() Colorado State 1-171% +5½ -115BetMGM | |||||||
![]() Colorado 1-257% -13 -110Caesars | |||||||
San Diego State 1-188% +13½ -110BetMGM | |||||||
#25USC 3-028% -18½ -105BetMGM | |||||||
![]() Hawaii 3-181% +3 -110Caesars | |||||||
![]() Charlotte 1-317 +2½ -115FanDuel |
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