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Nov 29, 2025 12:00 PM EST
Week 14
ISU
-14 (-105)o47½ (-110)
208, ESPNUMATCHUP
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Iowa State Cyclones vs Oklahoma State Cowboys Picks
Updated:Nov 25, 2025 1:19 AM EST
The upcoming Saturday football clash on November 29, 2025, between the Iowa State Cyclones and Oklahoma State Cowboys at Boone Pickens Stadium in Stillwater, OK, promises an exciting showdown in the 2025-26 NCAAF season. This game will be broadcast on ESPNU, making it accessible for fans and bettors alike to catch all the live action. Our picks favor Iowa State with a predicted score of 30-19, backing them on the moneyline and point spread markets with a -13.5 spread. The Cowboys are expected to put up a fight but fall short against the Cyclones' strong offense.
Our prediction model has been profitable in the last 10 games, boasting a hit rate of nearly 80% on 2-way markets including overtime, which is a solid indicator for bettors looking for reliable picks. Additionally, the point spread market for Oklahoma State has shown a positive EV of 4.3%, suggesting value in certain spread bets. These insights can help bettors make smart decisions when placing their bets on this exciting NCAAF matchup.
For more detailed analysis and to explore other picks in the league, visit our NCAAF picks page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
UPCOMING GAME PREDICTION
Spread
Money
OKSTSpread
CONSENSUS LINE
+13½ (-108)
PROJECTION
ISU (30) - OKST (19)
COVER PROBABILITY
EXPECTED VALUE
+3.6%
BET RATING
SEASON COVER %
4/11
36%
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NCAAF Week 14
NCAAF Tue 11/25
 Massachusetts 0-1174% +15 -115SugarHouse | |||||||
 Eastern Michigan 4-775% +7½ -109Caesars | |||||||
 Memphis 8-344% -4½ -113BetRivers | |||||||
 Buffalo 5-675% +7 -110Bet365 | |||||||
 Mississippi State 5-679% +7½ -120BetMGM | |||||||
 Nebraska 7-479% +6½ -112BetRivers | |||||||
 Northern Illinois 3-850% -4½ -112FanDuel | |||||||
 Kansas 5-671% +12½ -110BetMGM | |||||||
 Colorado State 2-950% +2½ -110FanDuel | |||||||
 #16Georgia Tech 9-267% +13½ -105FanDuel | |||||||
 New Mexico 8-389% +1½ -110Bet365 | |||||||
 North Texas 10-120% -19½ -110Bet365 | |||||||
 Utah State 6-589% +3½ -114Caesars | |||||||
 #17Texas 8-376% +2½ -104FanDuel | |||||||
 Purdue 2-980% +28½ -108Caesars | |||||||
 #25Arizona State 8-325% +2 -109Caesars | |||||||
 West Virginia 4-775% +24 -115SugarHouse | |||||||
 Florida Atlantic 4-786% +7 -105BetMGM | |||||||
 Louisville 7-425% -3 -110Bet365 | |||||||
 South Carolina 3-725% -2 -110Bet365 | |||||||
 #18Michigan 9-277% +10½ -114BetRivers | |||||||
 Pittsburgh 8-367% +7 -109Caesars | |||||||
 Central Michigan 7-467% +10½ -110BetMGM | |||||||
 Miami (OH) 6-5- -17½ -110Bet365 | |||||||
 Kansas State 5-633% -17 -110Bet365 | |||||||
 Baylor 5-643% -2½ -105Bet365 | |||||||
 Oklahoma State 1-10100% +14½ -115FanDuel | |||||||
 Delaware 5-60% -5 -110Bet365 | |||||||
 Sam Houston State 2-9100% +11 -115SugarHouse | |||||||
 #11Brigham Young 10-10% -17½ -110BetMGM | |||||||
 Marshall 5-60% -7 -110Bet365 | |||||||
 Old Dominion 8-350% -26½ -110BetMGM | |||||||
 Missouri State 7-425% -2½ -115Caesars | |||||||
 Jacksonville State 7-433% +2½ -105Bet365 | |||||||
 Appalachian State 5-6100% -2½ -109Caesars | |||||||
 Syracuse 3-8100% +3½ -122FanDuel | |||||||
 Tulsa 4-70% -8 -117SugarHouse | |||||||
 Texas State 5-60% -9½ -106Caesars | |||||||
 Louisiana 5-6- -10 -109Caesars | |||||||
 New Mexico State 4-750% -4 -115BetMGM | |||||||
 #20Tennessee 8-326% -2½ -110Bet365 | |||||||
 Duke 6-580% -1 -110Bet365 | |||||||
 Rutgers 5-6100% +13½ -114FanDuel | |||||||
 #8Oklahoma 9-215% -10 -107Caesars | |||||||
 UTSA 6-540% -6½ -120FanDuel | |||||||
 TCU 6-457% -3½ -110Caesars | |||||||
 Southern Miss 7-467% -6 -120SugarHouse | |||||||
 Arkansas 2-993% +2½ -104FanDuel | |||||||
 Minnesota 6-517% -1 -105Bet365 | |||||||
 Washington 8-381% +7 -117SugarHouse | |||||||
 Liberty 4-750% +2½ -110BetMGM | |||||||
 Coastal Carolina 6-5100% +22½ -110FanDuel | |||||||
 Florida 3-80% +1½ -115BetMGM | |||||||
 Washington State 5-633% -13½ -110Caesars | |||||||
 South Florida 8-30% -27 -110Bet365 | |||||||
 Michigan State 3-850% -3½ -110BetRivers | |||||||
 #19Virginia 9-225% -10 -112Caesars | |||||||
 North Carolina State 6-525% -7½ -105FanDuel | |||||||
 Auburn 5-6100% +6 -115SugarHouse | |||||||
 #24Tulane 9-20% -29½ -110BetMGM | |||||||
 #21Illinois 7-412% -6½ -115Bet365 | |||||||
 #15USC 8-260% -21½ -110FanDuel | |||||||
 California 6-589% +13½ -110BetMGM | |||||||
 Nevada 3-8100% +8½ -110Bet365 | |||||||
 San Jose State 3-875% +2½ -108FanDuel | |||||||
 Stanford 4-7100% +32½ -108Caesars | |||||||
 Hawaii 7-433% -7½ -113BetRivers |
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