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The Southern Miss Golden Eagles are set to take on the Louisiana Ragin' Cajuns in an exciting NCAAF matchup on October 18, 2025, at Cajun Field at Our Lady of Lourdes Stadium in Lafayette, LA. This Saturday football game will be broadcasted on ESPN+, offering fans a chance to catch all the action live. The Golden Eagles have been strong this season with a 4-2 record and are favorites at -4.0 on the spread. Quarterback play will be pivotal, with Southern Miss showcasing a potent passing game, averaging 247.167 yards per game. Louisiana, on the other hand, will rely on their defense to counter this threat, having allowed an average of 198.167 passing yards per game.
In their last encounter, the Golden Eagles emerged victorious with a scoreline of 23-13. Expect a competitive game as both teams have shown resilience, with Southern Miss slightly edging out in offensive stats. The Ragin' Cajuns will look to capitalize on their home field advantage and improve their 2-1 home record. The total points line is set at 54.5, indicating a potentially high-scoring affair. For those looking to place bets, the best odds for Southern Miss at -4.0 are available at Caesars. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
 Liberty 2-423% -10½ -105BetMGM | |||||||
 South Alabama 1-537% -6½ -122FanDuel | |||||||
 Western Kentucky 5-130% -7½ -110Caesars | |||||||
 Jacksonville State 3-380% +2½ -112FanDuel | |||||||
 Sam Houston State 0-667% +3 -117BetRivers | |||||||
 East Carolina 3-333% -16½ -110Caesars | |||||||
 #2Miami (FL) 5-019% -12½ -115FanDuel | |||||||
 Minnesota 4-289% +6½ -110Caesars | |||||||
 Utah State 3-343% -4 -110Caesars | |||||||
 California 4-20% -10½ -110Caesars | |||||||
 Miami (OH) 3-30% -12½ -110FanDuel | |||||||
 Boston College 1-540% -1½ -110Caesars | |||||||
 Duke 4-264% -2½ -115BetMGM | |||||||
 Bowling Green 3-30% -5½ -110FanDuel | |||||||
 #17Vanderbilt 5-167% -2½ -110Caesars | |||||||
 Michigan 4-253% -5½ -106FanDuel | |||||||
 Houston 5-125% -1½ -108FanDuel | |||||||
 TCU 4-220% -2½ -120FanDuel | |||||||
 Tulane 5-133% -10½ -110Caesars | |||||||
 South Carolina 3-3100% +5½ -110Caesars | |||||||
 UCF 3-350% -7 -110Caesars | |||||||
 Toledo 3-3- -24½ -110BetRivers | |||||||
 Massachusetts 0-6100% +17½ -115Caesars | |||||||
 Louisiana-Monroe 3-3- +6½ -110BetRivers | |||||||
 Northwestern 4-20% -3½ -110Caesars | |||||||
 Appalachian State 4-2- -11½ -110Caesars | |||||||
 Ohio 3-3- -11½ -115BetMGM | |||||||
 James Madison 5-10% -2 -110Caesars | |||||||
 Charlotte 1-5- +12½ -110FanDuel | |||||||
 Clemson 3-322% -9½ -110Caesars | |||||||
 #3Indiana 6-09% -26½ -113BetRivers | |||||||
 Marshall 3-360% +3½ -113BetRivers | |||||||
 Ball State 2-4- -1½ -105FanDuel | |||||||
 Boise State 4-267% -10½ -110Caesars | |||||||
 North Texas 5-150% -5½ -110Caesars | |||||||
 #9Georgia 5-130% -6½ -105BetMGM | |||||||
 Arkansas 2-475% +7½ -110Caesars | |||||||
 Wisconsin 2-485% +27½ -110Caesars | |||||||
 Air Force 1-50% -4½ -115FanDuel | |||||||
 UAB 2-4100% +21½ -110BetMGM | |||||||
 Arizona State 4-294% +10½ -110Caesars | |||||||
 Florida 2-4100% -9½ -112BetRivers | |||||||
 Louisiana 2-4- +4 -110Caesars | |||||||
 #18Virginia 5-10% -17½ -104FanDuel | |||||||
 Rutgers 3-3100% +15½ -110FanDuel | |||||||
 Georgia Southern 2-40% -6½ -113BetRivers | |||||||
 Colorado State 2-4100% +1 -117BetRivers | |||||||
 UCLA 2-467% -2½ -118FanDuel | |||||||
 Iowa 4-225% -2½ -118FanDuel | |||||||
 Kentucky 2-350% +12½ -115BetMGM | |||||||
 #19South Florida 5-1- -21½ -110BetMGM | |||||||
 Syracuse 3-3- +11½ -110Caesars | |||||||
 #13Notre Dame 4-244% -7½ -110FanDuel | |||||||
 #6Alabama 5-120% -8 -110Caesars | |||||||
 Auburn 3-375% -1½ -110BetRivers | |||||||
 Oklahoma State 1-5100% +21½ -112BetRivers | |||||||
 #15Brigham Young 6-00% +3½ -120FanDuel | |||||||
 New Mexico 3-30% -10 -110BetRivers | |||||||
 Oregon State 0-7- - | |||||||
 Stanford 2-4- +17½ -110Caesars |
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