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As we gear up for the exciting matchup on September 27, 2025, between the LSU Tigers and Ole Miss Rebels, fans and bettors alike are buzzing with anticipation. The game will be held at Vaught-Hemingway Stadium in Oxford, MS, and broadcasted on ABC and ESPN networks, offering ample opportunities for sports enthusiasts to catch the action live. LSU's recent performances have showcased their robust defensive strategies, particularly against pass offenses. However, Ole Miss boasts a formidable offensive lineup, with a strong run game that could pose challenges for LSU's defense. The Tigers, led by their starting quarterback, have shown resilience in past games, but they'll need to step up against Ole Miss's aggressive play. With the spread favoring Ole Miss at -1.5 and a total points line set at 55.5, bettors might find value in exploring LSU's potential for an upset. Past encounters, such as their close game on October 12, 2024, which LSU won 29-26, add an extra layer of intrigue to this contest. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
East Carolina 2-267% -3 -115BetMGM | |||||||
![]() Virginia 3-189% +7 -110BetMGM | |||||||
![]() Arizona State 3-180% -2½ -110Caesars | |||||||
![]() Oregon State 0-4100% +12½ -110BetMGM | |||||||
![]() Ohio 2-20% -10½ -110Caesars | |||||||
![]() Arkansas 2-275% +6 -110Caesars | |||||||
![]() Pittsburgh 2-167% +3½ -110FanDuel | |||||||
Syracuse 3-150% +5½ -105FanDuel | |||||||
![]() Wake Forest 2-1100% +15½ -115FanDuel | |||||||
Minnesota 2-1100% -5½ -110FanDuel | |||||||
![]() Kansas 3-117% -6 -110Caesars | |||||||
![]() North Texas 4-00% -12½ -115FanDuel | |||||||
![]() Kansas State 1-387% -5½ -115FanDuel | |||||||
#23Illinois 3-172% +6½ -110Caesars | |||||||
![]() #18Vanderbilt 4-00% -22½ -110Caesars | |||||||
Central Michigan 2-20% -5½ -110Caesars | |||||||
![]() James Madison 2-125% -15½ -110FanDuel | |||||||
![]() Louisiana-Monroe 2-1- -3 -110Caesars | |||||||
![]() Toledo 2-2- -20½ -110Caesars | |||||||
West Virginia 2-2100% +11½ -118FanDuel | |||||||
![]() Northern Illinois 1-2100% +3½ -124FanDuel | |||||||
![]() Boston College 1-240% -6 -113BetRivers | |||||||
Buffalo 2-2- +3 -115Caesars | |||||||
Iowa 3-167% +7 -105Caesars | |||||||
![]() Northwestern 1-2- -6½ -110Caesars | |||||||
Navy 3-0100% -14½ -108BetRivers | |||||||
Oklahoma State 1-2- +20½ -110Caesars | |||||||
![]() #13Ole Miss 4-029% -1½ -110Caesars | |||||||
#9Texas A&M 3-00% -6½ -110Caesars | |||||||
![]() Washington 3-087% +9½ -108BetRivers | |||||||
Miami (OH) 0-3- - | |||||||
Air Force 1-2- -4½ -110Caesars | |||||||
![]() New Mexico 2-1- -13½ -110BetRivers | |||||||
![]() Tulsa 2-2- +13½ -110Caesars | |||||||
![]() Mississippi State 4-0100% +8½ -110FanDuel | |||||||
![]() Old Dominion 2-1100% -15½ -110Caesars | |||||||
![]() Kennesaw State 2-2- -6½ -112BetRivers | |||||||
![]() Western Michigan 1-3- - | |||||||
![]() Florida Atlantic 1-2100% +13½ -105FanDuel | |||||||
![]() North Carolina State 3-10% -10½ -110Caesars | |||||||
Southern Miss 2-2- -3½ -110Caesars | |||||||
![]() #14Iowa State 4-025% -6 -110Caesars | |||||||
![]() Missouri State 2-2- +5½ -110Caesars | |||||||
![]() Boise State 2-1100% -17½ -105Caesars | |||||||
Stanford 1-3100% -1½ -110BetMGM | |||||||
![]() #20Missouri 4-0- -42½ -110BetMGM | |||||||
![]() Colorado State 1-2- -4½ -109BetRivers | |||||||
![]() #3Penn State 3-092% -3½ -105FanDuel | |||||||
![]() #5Georgia 3-033% -3 -110Caesars | |||||||
![]() South Carolina 2-233% -6½ -110Caesars | |||||||
![]() Louisiana 1-3- -2½ -110Caesars | |||||||
![]() UTEP 1-3100% +4 -110Caesars | |||||||
![]() Colorado 2-260% +6½ -110Caesars |
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