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The highly anticipated match-up between the Ole Miss Rebels and LSU Tigers is set to kick off on September 27, 2025, at Vaught-Hemingway Stadium in Oxford, MS. This clash promises to be an exciting display of college football as both teams bring their A-game to the field. The Ole Miss Rebels, boasting a strong home record, will look to capitalize on their offensive prowess, led by their dynamic quarterback. Meanwhile, the LSU Tigers, coming off a series of impressive wins, aim to maintain their dominance with a balanced attack strategy. Historically, these teams have always delivered thrilling encounters, and this game is expected to be no different.
In their last matchup on October 12, 2024, the Tigers narrowly defeated the Rebels 29-26. This season, the Rebels' high-powered offense will challenge the Tigers' defense, which has been formidable this season. With the game being broadcast on ABC and ESPN networks, fans can tune in to catch every moment of the action.
Betting trends show that the Rebels have been strong against the spread at home, making them a solid pick for bettors looking for value. The current odds spread and total points indicate a closely contested game, so analyzing game stats and betting insights is crucial for making informed wagers. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
![]() Charlotte 1-317 +2½ -115FanDuel | |||||||
Oklahoma State 1-212 -9½ -120FanDuel | |||||||
Rutgers 3-128 +2½ -114SugarHouse | |||||||
Army 1-238 +3 -113SugarHouse | |||||||
TCU 3-035 -6½ -110Caesars | |||||||
Miami (OH) 0-338 +1½ -105BetMGM | |||||||
Louisville 3-040 -26½ -110Caesars | |||||||
![]() Clemson 1-321 -17½ -107BetRivers | |||||||
![]() Wisconsin 2-210 -10 -115BetRivers | |||||||
![]() #16Utah 3-110 -3½ -105Bet365 | |||||||
![]() Memphis 4-032 +7½ -115Caesars | |||||||
![]() South Florida 3-163 -36 -110Caesars | |||||||
Virginia Tech 1-338 -34½ -110BetMGM | |||||||
#15Tennessee 3-156 -38½ -110Bet365 | |||||||
Central Michigan 2-249 -28½ -118FanDuel | |||||||
![]() #6Oregon 4-041 -32½ -105FanDuel | |||||||
Eastern Michigan 1-334 +2½ -110Caesars | |||||||
UCF 3-034 -7 -105Bet365 | |||||||
#7Florida State 3-066 -44½ -115FanDuel | |||||||
![]() Western Michigan 1-314 +13½ -110Caesars | |||||||
Buffalo 2-217 -5½ -110Caesars | |||||||
![]() #11Oklahoma 4-024 -6½ -110Caesars | |||||||
![]() #13Ole Miss 4-045 -11 -113BetRivers | |||||||
![]() Connecticut 2-231 -20½ -122FanDuel | |||||||
Nebraska 3-127 +1½ -115FanDuel | |||||||
#24Notre Dame 1-256 -24½ -110Caesars | |||||||
![]() Liberty 1-313 +8 -112BetRivers | |||||||
![]() Ohio 2-252 -30½ -110Bet365 | |||||||
![]() Duke 2-245 -3 -105Caesars | |||||||
![]() Mississippi State 4-038 -24 -105BetMGM | |||||||
![]() #18Georgia Tech 4-045 -24 -110BetMGM | |||||||
![]() San Jose State 1-231 -13½ -122FanDuel | |||||||
![]() Kansas 3-141 -11½ -117SugarHouse | |||||||
![]() Kennesaw State 2-228 +5 -113SugarHouse | |||||||
![]() Florida International 2-216 -4 -113BetRivers | |||||||
![]() Akron 1-351 -10½ -110Caesars | |||||||
![]() South Alabama 1-320 -14½ -110Caesars | |||||||
![]() #23Missouri 4-029 -9½ -117SugarHouse | |||||||
![]() Western Kentucky 3-131 -7½ -110Caesars | |||||||
Air Force 1-237 +11 -113BetRivers | |||||||
![]() Middle Tennessee 1-328 +3 -118BetRivers | |||||||
![]() Jacksonville State 2-245 -35½ -113BetRivers | |||||||
![]() Georgia Southern 2-245 -22 -112BetRivers | |||||||
![]() Missouri State 2-242 -14½ -109BetRivers | |||||||
East Carolina 2-213 +7 -124SugarHouse | |||||||
![]() #4Miami (FL) 4-026 -8 -114SugarHouse | |||||||
![]() #19Indiana 4-063 -6½ -120FanDuel | |||||||
Baylor 2-224 -2½ -104FanDuel | |||||||
![]() Virginia 3-148 -16½ -110Caesars | |||||||
![]() Louisiana Tech 3-130 -3 -110Bet365 | |||||||
![]() Washington State 2-224 +21 -110Caesars | |||||||
![]() #20Vanderbilt 4-070 -27 -110Caesars | |||||||
#3LSU 4-056 -48½ -108FanDuel | |||||||
![]() #8Texas 3-155 -39½ -110Caesars | |||||||
![]() Utah State 3-148 -23½ -115BetMGM | |||||||
Texas State 3-135 -32½ -110Caesars | |||||||
![]() UTEP 1-325 -5 -115BetRivers | |||||||
![]() Colorado State 1-216 +5½ -110Caesars | |||||||
![]() Colorado 2-237 -11 -120SugarHouse | |||||||
San Diego State 2-134 +14 -105Caesars | |||||||
#25USC 4-045 -18½ -115FanDuel | |||||||
![]() Hawaii 3-221 +2½ -105BetMGM |
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