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The Saturday football clash on October 18, 2025, between the Michigan State Spartans and Indiana Hoosiers at Memorial Stadium in Bloomington, IN, is set for a 3:30 PM ET kickoff. Broadcast live on peacock for this key NCAAF showdown, expect a rowdy home crowd as the Hoosiers aim to extend their undefeated home streak.
This matchup offers distinct betting trends and valuable betting insights. Indiana’s offense is humming, averaging 502.8 total yards per game, including 261.2 passing yards, while Michigan State’s defense concedes 369.2 yards per contest and 238.0 through the air. Conversely, the Spartans put up 331.7 total yards with a 200.5-yard passing attack against a Hoosiers defense allowing just 142.2 passing yards per game.
On the ground, the Hoosiers roll for 241.7 rushing yards per game against a Spartans defense giving up 131.2 yards, while Michigan State’s 131.2-yard ground game faces Indiana’s stingy rush defense holding foes to 86.8 yards.
Hoosiers’ offensive line allows just one sack per game versus Michigan State’s defensive front registering 2.17 sacks. Both teams start their usual first-string quarterbacks under center, and in their last matchup on November 2, 2024, Indiana dominated 47-10 as noted in the last matchup. Indiana is 4-2-0 ATS (3-1 at home); check the NCAAF standings page for full ATS records.
The Hoosiers are 27-point favorites at -110, with a 52.5-point total at Caesars. This spread reflects Indiana’s offensive edge and a stout defense. These stats can guide bettors toward taking Indiana -27, leveraging home-field dominance and matchup advantages to make a smart wager. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
![]() Liberty 2-434% -9½ -115FanDuel | |||||||
![]() South Alabama 1-542% -7½ -105Caesars | |||||||
![]() Western Kentucky 5-116% -8½ -115FanDuel | |||||||
![]() Jacksonville State 3-357% +2½ -108FanDuel | |||||||
![]() Sam Houston State 0-650% +3 -114Caesars | |||||||
East Carolina 3-340% -16½ -110Caesars | |||||||
![]() #2Miami (FL) 5-026% -13½ -115BetRivers | |||||||
Minnesota 4-257% +9½ -115FanDuel | |||||||
![]() Utah State 3-327% -3½ -110Caesars | |||||||
![]() California 4-218% -9½ -110BetMGM | |||||||
Miami (OH) 3-30% -12½ -110FanDuel | |||||||
![]() Boston College 1-562% -1½ -110Bet365 | |||||||
![]() Duke 4-272% -1½ -110Caesars | |||||||
Bowling Green 3-337% -3½ -112BetRivers | |||||||
![]() #17Vanderbilt 5-161% -2½ -110Caesars | |||||||
![]() Michigan 4-248% -5½ -114SugarHouse | |||||||
![]() Houston 5-130% -1½ -108FanDuel | |||||||
TCU 4-242% -2½ -120FanDuel | |||||||
Tulane 5-123% -9½ -110Bet365 | |||||||
![]() South Carolina 3-388% +5½ -110Caesars | |||||||
UCF 3-317% -7 -114Caesars | |||||||
![]() Toledo 3-3100% -24½ -113BetRivers | |||||||
![]() Massachusetts 0-6100% +17½ -115BetMGM | |||||||
![]() Louisiana-Monroe 3-3100% +6½ -110BetRivers | |||||||
![]() Northwestern 4-243% -3½ -105BetMGM | |||||||
Appalachian State 4-20% -10 -110BetRivers | |||||||
![]() Ohio 3-30% -11 -110Caesars | |||||||
![]() James Madison 5-10% -1½ -110BetRivers | |||||||
![]() Charlotte 1-5100% +11½ -110Caesars | |||||||
![]() Clemson 3-328% -8½ -112BetRivers | |||||||
![]() #3Indiana 6-015% -26½ -114FanDuel | |||||||
Marshall 3-371% +2½ -107Caesars | |||||||
Ball State 2-40% -1½ -105FanDuel | |||||||
![]() Boise State 4-260% -10½ -112BetRivers | |||||||
![]() North Texas 5-150% -4½ -108FanDuel | |||||||
![]() #9Georgia 5-148% -7 -115Caesars | |||||||
![]() Arkansas 2-483% +8 -115SugarHouse | |||||||
![]() Wisconsin 2-494% +26½ -110BetMGM | |||||||
Air Force 1-525% -4½ -110Bet365 | |||||||
UAB 2-430% +21½ -110Caesars | |||||||
![]() Arizona State 4-243% +12½ -114SugarHouse | |||||||
Florida 2-433% -8½ -110BetMGM | |||||||
![]() Louisiana 2-450% +4 -109Caesars | |||||||
![]() #18Virginia 5-10% -17½ -104FanDuel | |||||||
Rutgers 3-3100% +18 -122BetRivers | |||||||
![]() Georgia Southern 2-40% -6½ -110Bet365 | |||||||
![]() Colorado State 2-4100% -2 -109BetRivers | |||||||
UCLA 2-437% -3 -112BetRivers | |||||||
Iowa 4-281% -2½ -115FanDuel | |||||||
Kentucky 2-386% +12½ -113BetRivers | |||||||
![]() #19South Florida 5-10% -21½ -110Caesars | |||||||
Syracuse 3-30% +11½ -110BetRivers | |||||||
#13Notre Dame 4-258% -9 -113BetRivers | |||||||
#6Alabama 5-124% -7½ -114SugarHouse | |||||||
Auburn 3-376% +2½ -115SugarHouse | |||||||
Oklahoma State 1-5100% +22½ -115BetMGM | |||||||
#15Brigham Young 6-036% +3½ -110Caesars | |||||||
![]() New Mexico 3-30% -11½ -110Caesars | |||||||
![]() Oregon State 0-7- - | |||||||
Stanford 2-480% +18 -110Caesars |
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