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The upcoming clash on November 22, 2025, between the USC Trojans and Oregon Ducks at Autzen Stadium in Eugene, OR, is set to be a thrilling Saturday football matchup in the 2025-26 NCAAF season. Broadcasting live on CBS, this game offers bettors a prime opportunity to engage with competitive odds and betting lines.
Currently, the Oregon Ducks are favored with a point spread of -9½ -107, while the USC Trojans sit at +9½ -113 according to Caesars sportsbook. Opening lines were similar, indicating steady confidence in the Ducks' edge. The total points line is set at 59½ with the over at -117 and the under at -105, highlighting expectations for a high-scoring game. Understanding these betting odds and how they have moved can help bettors make informed decisions and spot value bets.
For those looking to dive deeper, the NCAAF odds page provides comprehensive insights. Plus, you can start your OddsTrader Turbo subscription to get an edge on the market or place your bets with a trusted U.S. regulated sportsbook like Caesars for the best available odds. This matchup at Autzen Stadium is a must-watch for football fans and bettors alike.
![]() Ohio 6-423% -33 -110Bet365 | |||||||
Bowling Green 3-748% -2½ -118FanDuel | |||||||
![]() Northern Illinois 3-757% +7 -117BetRivers | |||||||
Buffalo 5-550% +1½ -110Bet365 | |||||||
![]() Kent State 4-681% +9½ -105Bet365 | |||||||
Arkansas State 5-50% -2½ -117Caesars | |||||||
![]() North Carolina State 5-564% +5 -118BetRivers | |||||||
UNLV 8-211% -2½ -110FanDuel | |||||||
![]() #1Ohio State 10-040% -30½ -114FanDuel | |||||||
Army 5-450% -9½ -120FanDuel | |||||||
![]() Wake Forest 7-318% -17 -109BetRivers | |||||||
Virginia Tech 3-775% +18 -117SugarHouse | |||||||
![]() #11Oklahoma 8-236% -7½ -105BetMGM | |||||||
SMU 7-313% -2½ -124FanDuel | |||||||
![]() Iowa State 6-40% -4 -114BetRivers | |||||||
![]() Northwestern 5-50% -3½ -110Bet365 | |||||||
#3Texas A&M 10-0- - | |||||||
![]() #5Georgia 9-155% -43½ -115FanDuel | |||||||
![]() Georgia Southern 5-567% +12½ -110Bet365 | |||||||
![]() James Madison 9-122% -12½ -115FanDuel | |||||||
![]() Arizona 7-314% -6½ -110Bet365 | |||||||
![]() Toledo 6-450% -27 -110BetRivers | |||||||
Wyoming 4-60% -6½ -110Bet365 | |||||||
![]() Kennesaw State 7-317% -6½ -105FanDuel | |||||||
#4Alabama 8-2- - | |||||||
Auburn 4-6- - | |||||||
Appalachian State 4-686% +4½ -109Caesars | |||||||
![]() Florida Atlantic 4-683% +7½ -115Bet365 | |||||||
![]() UTEP 2-840% -3 -110Bet365 | |||||||
![]() Middle Tennessee 1-917% -6½ -115BetMGM | |||||||
![]() Louisiana Tech 5-50% +1½ -118FanDuel | |||||||
UAB 3-775% +21½ -109Caesars | |||||||
![]() North Carolina 4-689% +7 -114BetRivers | |||||||
![]() #10Texas 7-310% -8½ -110FanDuel | |||||||
![]() #8Oregon 9-141% -9½ -115BetMGM | |||||||
#21Iowa 6-422% -16½ -110Bet365 | |||||||
![]() UTSA 5-5100% +2½ -105BetMGM | |||||||
![]() #14Vanderbilt 8-218% -8½ -118SugarHouse | |||||||
![]() South Alabama 3-7100% +2½ -110FanDuel | |||||||
![]() Florida International 5-50% +1½ -120BetMGM | |||||||
#9Notre Dame 8-233% -35 -110Bet365 | |||||||
Temple 5-587% +8½ -113BetRivers | |||||||
UCF 4-640% -14 -105BetMGM | |||||||
Maryland 4-6100% +13½ -105BetMGM | |||||||
![]() Houston 8-20% -1 -114BetRivers | |||||||
![]() #13Utah 8-210% -17 -120Bet365 | |||||||
Troy 6-433% -11 -110Bet365 | |||||||
![]() South Carolina 3-725% -23½ -110FanDuel | |||||||
![]() Clemson 5-5- - | |||||||
Texas State 4-6- -17½ -110Bet365 | |||||||
![]() #16Georgia Tech 9-16% -2½ -110Bet365 | |||||||
![]() Penn State 4-625% -9½ -110Caesars | |||||||
![]() Boise State 6-40% -16½ -110Bet365 | |||||||
Air Force 3-7100% +3½ -114Caesars | |||||||
Florida 3-782% +5 -120BetRivers | |||||||
Stanford 3-791% +3 -109Caesars | |||||||
![]() Wisconsin 3-7100% +8½ -105FanDuel | |||||||
Rice 5-560% +18½ -110Bet365 | |||||||
LSU 6-433% -21½ -110Bet365 | |||||||
![]() #25Cincinnati 7-395% +3 -122SugarHouse | |||||||
![]() Colorado 3-789% +7½ -115Bet365 | |||||||
UCLA 3-775% +10½ -108Caesars | |||||||
San Diego State 8-20% -11½ -110BetMGM | |||||||
![]() Fresno State 7-30% -2½ -113SugarHouse |
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