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Nov 15, 2025 2:00 PM EST
Week 12
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Western Illinois Leathernecks vs Southeast Missouri State Redhawks Picks
Updated:Nov 14, 2025 3:11 AM EST
The upcoming Saturday football game on November 15, 2025, features the Western Illinois Leathernecks hosting the Southeast Missouri State Redhawks at Hanson Field in Macomb, IL. This NCAAF regular season Week 12 matchup promises exciting action for fans and bettors alike. The game will be broadcast on ESPN+, giving viewers a great opportunity to catch all the live action.
Our expert picks for this Western Illinois Leathernecks vs Southeast Missouri State Redhawks game predict a close contest with Southeast Missouri State edging out Western Illinois with a final score prediction of 28-24. We lean towards Southeast Missouri State with a moneyline bet for the best value. Historically, our prediction model has been profitable in recent games, boasting a strong hit rate in point spread bets, particularly with Southeast Missouri State covering the spread in 57.4% of their recent games and showing positive expected value. This statistical edge can help bettors make smarter decisions for this matchup.
For bettors looking to capitalize on this game, consider our betting tips that focus on point spread markets which have shown the highest EV and hit rate. This approach has yielded consistent profits in the last 10 games, making it a reliable choice for this contest. To explore more insights and find additional picks, check out our NCAAF picks page and enhance your betting strategy. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook to profit off the edge.
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NCAAF Week 12
NCAAF Fri 11/14
 #20Louisville 7-29 PK -115 | |||||||
 #8Oregon 8-1 0 -25½ -112 | |||||||
 Connecticut 7-325% -7½ -105FanDuel | |||||||
 Charlotte 1-893% +18½ -110FanDuel | |||||||
 #25Cincinnati 7-223% -6 -110Bet365 | |||||||
 Navy 7-224% +10½ -114BetRivers | |||||||
 #2Indiana 10-016% -29 -108Caesars | |||||||
 #22Pittsburgh 7-270% +12½ -110Caesars | |||||||
 Ball State 4-587% +2½ -106Caesars | |||||||
 Oklahoma State 1-871% +19½ -109Caesars | |||||||
 #3Texas A&M 9-070% -17½ -110FanDuel | |||||||
 Northwestern 5-446% +10½ -110BetMGM | |||||||
 LSU 5-422% -5 -114SugarHouse | |||||||
 Tulsa 2-741% +2½ -106FanDuel | |||||||
 Arizona State 6-311% -11 -114SugarHouse | |||||||
 Kentucky 4-5- -21½ -110Bet365 | |||||||
 Georgia State 1-878% +8 -113BetRivers | |||||||
 UAB 3-679% +18½ -115FanDuel | |||||||
 New Mexico 6-315% -14 -115BetRivers | |||||||
 Missouri State 6-35% -4½ -105FanDuel | |||||||
 James Madison 8-167% -21 -109Caesars | |||||||
 Boston College 1-953% +17 -115SugarHouse | |||||||
 Duke 5-446% -3½ -110BetMGM | |||||||
 #15Miami (FL) 7-27% -14½ -113BetRivers | |||||||
 Michigan State 3-678% +7½ -114FanDuel | |||||||
 #4Alabama 8-115% -5½ -113BetRivers | |||||||
 Southern Miss 7-235% -3 -110BetMGM | |||||||
 #6Texas Tech 9-186% -23½ -110BetMGM | |||||||
 Louisiana-Monroe 3-667% +4½ -105FanDuel | |||||||
 Illinois 6-318% -15 -113BetRivers | |||||||
 #17USC 7-225% -6 -117SugarHouse | |||||||
 Western Kentucky 7-20% -13 -121SugarHouse | |||||||
 Nevada 1-892% +9½ -104FanDuel | |||||||
 East Carolina 6-374% -2½ -124FanDuel | |||||||
 Tulane 7-225% -17½ -110Caesars | |||||||
 #23Tennessee 6-31% -39½ -110BetMGM | |||||||
 Wake Forest 6-344% -5½ -107Caesars | |||||||
 Florida International 4-583% +3 -118BetRivers | |||||||
 Georgia Southern 4-540% -3 -114Caesars | |||||||
 Sam Houston State 1-886% +10½ -102Caesars | |||||||
 Baylor 5-483% +9 -114BetRivers | |||||||
 #7Ole Miss 9-115% -11½ -105BetMGM | |||||||
 Washington 6-39% -16½ -110Bet365 | |||||||
 UNLV 7-211% -6 -110Bet365 | |||||||
 #5Georgia 8-166% -6 -110Bet365 | |||||||
 Florida State 4-519% -13½ -115BetRivers | |||||||
 #1Ohio State 9-036% -31½ -105Bet365 | |||||||
 Missouri 6-329% -6½ -118FanDuel | |||||||
 Jacksonville State 6-382% +3½ -118FanDuel | |||||||
 Washington State 4-514% -7½ -115Bet365 | |||||||
 #12Brigham Young 8-110% -3 -110Caesars | |||||||
 Fresno State 6-328% -3½ -105BetMGM | |||||||
 San Diego State 7-236% -1½ -112FanDuel | |||||||
 Akron 4-735 -7 -118SugarHouse | |||||||
 Western Michigan 6-417 +2 -139SugarHouse | |||||||
 Massachusetts 0-103 +10 -110BetMGM | |||||||
 Miami (OH) 5-53 +5½ -105Bet365 | |||||||
 Central Michigan 6-438 -2½ -110BetMGM | |||||||
 Old Dominion 7-333 -9 -115BetRivers |
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