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FINAL
Oct 25, 2025 3:30 PM EDT
BYU 41 vs ISU 27
Week 9
12-2
#10 Brigham Young
41
FINAL
27
8-4
Iowa State
ISU
-2½ (-118)o49 (-107)
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BYU Cougars vs Iowa State Cyclones Picks

Updated:Oct 25, 2025 2:39 AM EDT

The upcoming NCAAF showdown on October 25, 2025, features the BYU Cougars visiting the Iowa State Cyclones at Jack Trice Stadium in Ames, IA. This Saturday football game promises to be an exciting contest broadcasted on Fox, where bettors can find valuable picks and betting tips to capitalize on the action.

Our prediction model, which has been profitable in recent games with a strong hit rate on point spread bets, forecasts a close game with BYU winning 27 to 25 against Iowa State. The model shows a 55% coverage percentage and a positive EV of 2.8% backing BYU with a 2.5-point spread. Total points are predicted to be just under 51, suggesting a moderately tight game.

For bettors looking for smart wagering strategies, these insights provide a clear edge, especially given our recent successful picks in similar markets. Check out our detailed NCAAF picks and predictions to make informed bets. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.

What is the predicted score for the game?
UPCOMING GAME PREDICTION
Spread
Money
Total
team
BYUSpread
CONSENSUS LINE
+3 (-114)
PROJECTION
BYU (27) - ISU (25)
COVER PROBABILITY
56%
EXPECTED VALUE
+2.7%
BET RATING
SEASON COVER %
5/7
71%
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