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FINAL
Nov 1, 2025 12:00 PM EDT
DUKE 46 vs CLEM 45
Week 10
CLEM
-4 (-110)o54½ (-117)
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Betting Trends Duke Blue Devils vs Clemson Tigers
Updated:Nov 1, 2025 3:37 AM EDT
The upcoming Saturday football showdown on November 1, 2025, features the Duke Blue Devils visiting the Clemson Tigers at Memorial Stadium in Clemson, SC. This NCAAF regular-season Week 10 matchup promises intense action as both teams look to improve their standings in the league. The game will be broadcast on the ACC Network, providing excellent coverage for fans and bettors alike.
Clemson enters this game as a slight favorite with a -3.5 point spread and odds of -105 at Caesars sportsbook, while Duke is the underdog at +3.5 and +143 odds. The total points line is set at 54.5, hinting at a moderately high-scoring contest. Clemson's offensive stats are impressive, averaging 400.7 total yards per game, with strong passing yards (284.3) and a balanced rushing attack (116.4 yards). Defensively, Clemson allows about 337.6 yards per game, with particular strength in pass defense, allowing 227.9 passing yards on average.
Duke, on the other hand, boasts an even more potent offense, averaging 463.3 total yards per game, with a strong passing game (319 yards) and a solid rushing attack (144.3 yards). Defensively, Duke allows 375.9 yards per game, with vulnerabilities in pass defense (245.9 passing yards allowed), which Clemson may look to exploit. The starting quarterbacks for both teams are expected to play, with no major injury concerns reported, giving bettors confidence in assessing betting trends.
Recent performances show Clemson with a mixed record, including a loss to SMU 35-24 and a strong win against Boston College 41-10. Duke has had a more consistent run, including a dominant 38-3 victory over Syracuse and a solid 45-21 win against California. These game stats and betting insights suggest a competitive matchup with Clemson's home advantage at Memorial Stadium and Duke's high-powered offense in focus.
The last matchup on September 4, 2023, saw Duke defeat Clemson 28-7, which could influence betting trends as bettors weigh past performances. The point spread and total points line are crucial factors for bettors to consider, with the spread favoring Clemson by 3.5 points and a total of 54.5 points set for the game. These stats offer valuable sports insights for making smart betting decisions.
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All
6-7-1 (169th)Against the Spread5-8 (217th)
9-5 (82nd)Straight Up7-6 (121st)
+1.3Straight Up Units-2.7
10-4Over / Under5-8
OFF
DEF
OFF
DEF
34.6Points27.2
423.5Total Yards392.2
6.1Yards Per Play5.6
285.4Passing Yards267.8
24 - 36.1 (66.4%)Completions-Attempts23.8 - 36.5 (65.1%)
7.9Yards Per Passing Play7.3
14.2Sacks-Yards Lost11.8
138.1Rushing Yards124.5
32.5Attempts31.5
4.3Yards Per Rush3.9
22.61st Downs21.1
12.6Passing11.8
7.6Rushing7.5
2.4Penalties1.8
5.1 / 13 (39%)3rd Down4.6 / 13.5 (34.3%)
2.2 / 3.1 (72.1%)4th Down1.5 / 2.8 (55.6%)
3.9 / 4.7 (83.3%)Red Zone2.5 / 3.2 (78.6%)
6.4 (62.4)Penalties (Yards)4.4 (42.1)
0.4Interceptions0.5
0.5Fumbles Lost0.6
70.6Total Plays69.7
6.3Kickoffs5.5
1.6Returns1.1
46.6Yards20.5
29.6Yards Per Return19
3.2Punts4.2
0.6Returns1.4
8.3Yards10.1
12.9Yards Per Return7.3
HEAD TO HEAD
221, CBS Sports Netwo
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NCAAFWeek 1
NCAAF Sat 08/29
 TCU - -6½ -110Bovada | |||||||
 Valparaiso - - | |||||||
 USC - -35½ -108Heritage | |||||||
 Virginia - -3 -110MyBookie | |||||||
 North Dakota State - -8½ -105BetOnline | |||||||
 Eastern Michigan - -7½ -110Bovada | |||||||
 Florida State - -30½ -108Heritage | |||||||
 Stanford - -3½ -108Heritage | |||||||
 UNLV - -3 -115Bookmaker | |||||||
 Rutgers - -30½ -108Heritage | |||||||
 Wake Forest - -22½ -108Heritage | |||||||
 Kennesaw State - - | |||||||
 Buffalo - - | |||||||
 Delaware - - | |||||||
 UCF - - | |||||||
 Georgia Tech - -7 -110BetOnline | |||||||
 Minnesota - - | |||||||
 Missouri - - | |||||||
 Illinois - -27½ -108Heritage | |||||||
 Utah - - | |||||||
Eastern Michigan - -3½ -108Heritage | |||||||
 Georgia State - - | |||||||
 Purdue - - | |||||||
 Michigan State - -10½ -105BetOnline | |||||||
 Kansas - - | |||||||
USC - -22½ -110BetOnline | |||||||
Stanford - +23 -105BetOnline | |||||||
 West Virginia - -17½ -105BetOnline | |||||||
 James Madison - -6 -110BetOnline | |||||||
 Indiana - -39½ -108Heritage | |||||||
 Alabama - -26½ -108Heritage | |||||||
 Nebraska - -23½ -105BetOnline | |||||||
 Houston - -18½ -108Heritage | |||||||
 Connecticut - - | |||||||
 Syracuse - - | |||||||
 Bowling Green - - | |||||||
 Army - - | |||||||
 Pittsburgh - -15½ -110Bovada | |||||||
 Ohio State - -49½ -110BetOnline | |||||||
 South Carolina - -34½ -108Heritage | |||||||
 Oklahoma - -40½ -105BetOnline | |||||||
 Iowa State - - | |||||||
 Kentucky - - | |||||||
 Air Force - - | |||||||
 Temple - - | |||||||
 Georgia - - | |||||||
 Cincinnati - -7½ -108Heritage | |||||||
 Penn State - -22½ -110BetOnline | |||||||
 Duke - -8 -110Bookmaker | |||||||
 Texas - -30½ -110BetOnline | |||||||
 Oregon - -24½ -108Heritage | |||||||
 Auburn - -7 -105Bookmaker | |||||||
 Tennessee - - | |||||||
 Appalachian State - - | |||||||
 Charlotte - - | |||||||
 UTSA - - | |||||||
North Dakota State - - | |||||||
 Navy - - | |||||||
 Tulsa - +12½ -108Heritage | |||||||
 Iowa - -30 -110Bookmaker | |||||||
 Arkansas - - | |||||||
 Southern Miss - - | |||||||
 Colorado State - -3½ -108Heritage | |||||||
 Old Dominion - - | |||||||
 South Florida - -12 -108Heritage | |||||||
 Texas A&M - -38½ -110BetOnline | |||||||
 Troy - -17 -112Bookmaker | |||||||
 Memphis - -10½ -108Heritage | |||||||
 South Alabama - - | |||||||
 Middle Tennessee - - | |||||||
 Kansas State - - | |||||||
 Utah State - - | |||||||
 Jacksonville State - - | |||||||
 Vanderbilt - - | |||||||
 Georgia Southern - - | |||||||
 Texas Tech - - | |||||||
 Rice - - | |||||||
 Michigan - -26½ -108Heritage | |||||||
 Mississippi State - -28 -110Bookmaker | |||||||
 LSU - -11 -110MyBookie | |||||||
 Virginia Tech - - | |||||||
 Louisiana Tech - - | |||||||
 Florida - -26 -110BetOnline | |||||||
 Northwestern - - | |||||||
 Louisiana - - | |||||||
 Maryland - - | |||||||
 Brigham Young - - | |||||||
 New Mexico State - - | |||||||
 Arizona - - | |||||||
 San Diego State - - | |||||||
 New Mexico - -12 -108Heritage | |||||||
 Hawaii - +2½ -110MyBookie | |||||||
 Arizona State - - | |||||||
 Sacramento State - - | |||||||
 California - PK -110BetOnline | |||||||
 Nevada - +3½ -115BetOnline | |||||||
 Washington - -21½ -108Heritage | |||||||
 Notre Dame - -20½ -104Bookmaker | |||||||
 Ole Miss - -4½ -110BetOnline | |||||||
Florida State - +3 -115BetOnline |
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