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The highly anticipated matchup between the North Carolina State Wolfpack and the Duke Blue Devils is set for September 20, 2025, at Brooks Field at Wallace Wade Stadium in Durham, NC. As part of the NCAAF series, this Saturday football event is sure to attract a lot of attention. The game will be broadcasted on ESPN2, providing a great opportunity for fans and bettors alike to tune in. Current odds show Duke as the favorite with a point spread of -3 -108 at Caesars, while NC State is at +3 -115. The Moneyline offers Duke at -152 and NC State at +125, indicating a closely contested game. The over/under is set at 57, with the over at -112 and the under at -108. Understanding these odds can help bettors make smarter decisions. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. For more detailed betting odds and lines, check out our NCAAF odds page.