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FINAL
Nov 22, 2025 3:30 PM EST
MSU 17 vs IOWA 20
Week 13
IOWA
-17 (-110)o42½ (-110)
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Michigan State Spartans vs Iowa Hawkeyes Picks
Updated:Nov 22, 2025 1:58 AM EST
The upcoming Saturday football game on November 22, 2025, features an exciting NCAAF matchup between the Michigan State Spartans and the Iowa Hawkeyes. This highly anticipated regular season Week 13 game will be held at Kinnick Stadium in Iowa City, IA, broadcasting live on Fox Sports 1. Bettors looking for insightful picks and predictions will find valuable information to place smart bets.
Our prediction model favors the Iowa Hawkeyes with a predicted score of 30 against Michigan State's 16, suggesting a strong likelihood of Iowa covering the -16.5 point spread. The total score is projected to be around 45, slightly over the 42.5 line, with an over bet showing a 54.2% cover rate and positive expected value (EV) of 0.9%, indicating a profitable opportunity. The model's hit rate and EV metrics have been solid, with recent bets on point spreads and totals delivering consistent results for bettors.
The Iowa Hawkeyes have demonstrated strong performance in recent games, with notable wins against quality opponents, while Michigan State has shown resilience but struggles to maintain consistency. These insights can help bettors make well-informed decisions. For more details and to explore additional NCAAF picks, check out the comprehensive NCAAF picks and predictions page.
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UPCOMING GAME PREDICTION
Spread
Money
Total
MSUSpread
CONSENSUS LINE
+17 (-109)
PROJECTION
MSU (15) - IOWA (29)
COVER PROBABILITY
EXPECTED VALUE
+5.1%
BET RATING
SEASON COVER %
5/10
50%
NCAAF
Spread
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Top 25
Top 25
Div. II & III
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