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FINAL OT
Oct 4, 2025 3:30 PM EDT
UVA 30 vs LOU 27
Week 6
11-3
#19 Virginia
30
FINAL
27
9-4
Louisville
LOU
-6 (-115)o60 (-110)
tvESPN2, 209, ESPN Networks
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Virginia Cavaliers vs Louisville Cardinals Odds

Updated:Oct 4, 2025 3:10 AM EDT

Before the game, the Virginia Cavaliers are set to face the Louisville Cardinals on October 4, 2025, in a thrilling NCAAF clash at L&N Federal Credit Union Stadium in Louisville, KY. This Saturday football match is a must-watch, airing on ESPN2. The Louisville Cardinals have the upper hand with a point spread of -6½ -115, indicating their favorite status. Meanwhile, the Virginia Cavaliers are at +6½ -105, making them the underdogs. As bettors eye the odds, it's crucial to understand the dynamics of this game. The current point spread has shifted slightly from the opening odds, reflecting changes in team performances and public sentiment. This matchup not only captivates fans but offers enticing betting lines. Explore more NCAAF odds to make informed wagers. Ready to leverage insights? Start your OddsTrader Turbo subscription today for a competitive edge!

Where can I watch the Virginia Cavaliers vs Louisville Cardinals game?
Spread (FULL GAME)
EXPECTED VALUECOVER PROB.EXPECTED VALUEBEST LINE
team
VirginiaSpread
+4.1%
EV
+4.1%
55%
team
LouisvilleSpread
-8.1%
EV
-8.1%
45%
MONEYLINE (FULL GAME)
EXPECTED VALUECOVER PROB.EXPECTED VALUEBEST LINE
team
VirginiaMONEYLINE
+7.5%
EV
+7.5%
41%
team
LouisvilleMONEYLINE
-10.6%
EV
-10.6%
59%
Total (FULL GAME)
BEST LINE
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UNDERTotal
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LouisvilleSpread
MONEYLINE (1H)
BEST LINE
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LouisvilleMONEYLINE
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LouisvilleSpread
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LouisvilleMONEYLINE
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Spread (1Q)
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VirginiaSpread
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LouisvilleSpread
MONEYLINE (1Q)
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Spread (3Q)
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LouisvilleSpread
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Spread (4Q)
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The best odds available today for Virginia is +6½ -105 at BetAnything and for Louisville -6 -115 at BetOnline. The total for the over/under line is o60 -110 at BetOnline.
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