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FINAL
Nov 22, 2025 12:00 PM EST
MIZZ 6 vs OKLA 17
Week 13
OKLA
-4½ (-105)o42½ (-115)
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Missouri Tigers vs Oklahoma Sooners Picks
Updated:Nov 22, 2025 2:52 AM EST
The upcoming Saturday football game on November 22, 2025, between the Missouri Tigers and Oklahoma Sooners promises an exciting NCAAF showdown at Gaylord Family Oklahoma Memorial Stadium in Norman, OK. Fans and bettors alike will be tuning in on ABC and ESPN networks to catch all the action live.
Our expert picks and betting tips for Missouri Tigers vs Oklahoma Sooners highlight a predicted final score of 24-21 in favor of the Sooners. The point spread leans towards Oklahoma at -5.5, with a solid 52.6% cover percentage on Missouri +5.5 for bettors looking to hedge. The total points are expected to go over 42.5, with a predicted total score of approximately 44.9, offering high expected value (EV) for over bets at 2.9% and a hit rate of 54.3% in recent games.
Our prediction model has been profitable over the last 10 games, especially with the American Total market, which has a positive EV and a hit rate above 50%. This insight can help bettors make smarter decisions by understanding where the edge lies. For comprehensive NCAAF picks and more detailed betting strategies, check out our NCAAF picks and predictions.
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UPCOMING GAME PREDICTION
Spread
Money
Total
MIZZSpread
CONSENSUS LINE
+4½ (-108)
PROJECTION
OKLA (24) - MIZZ (21)
COVER PROBABILITY
EXPECTED VALUE
-1.1%
BET RATING
SEASON COVER %
6/10
60%
NCAAF
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