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FINAL
Nov 7, 2025 9:00 PM EST
NW 17 vs USC 38
Week 11
7-6
Northwestern
17
FINAL
38
9-4
#19 USC
USC
-14 (-116)o55 (-107)
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Northwestern Wildcats vs USC Trojans Odds

Updated:Nov 7, 2025 2:33 AM EST

The upcoming Friday football game on November 7, 2025, features the Northwestern Wildcats visiting the USC Trojans at the iconic Los Angeles Memorial Coliseum in Los Angeles, CA. This NCAAF matchup promises excitement and strategic betting opportunities for fans and bettors alike.

Currently, the point spread odds favor the USC Trojans at -14½ -105, with the Northwestern Wildcats as underdogs at +14½ -115, according to Caesars sportsbook. The opening spread was the same, indicating stable betting lines with no significant movement so far. The over/under total is set at 51 points with odds of -110 on both the over and under.

This game is broadcasted on Fox, making it accessible for fans eager to watch the action live. Understanding these betting odds and point spread can help bettors make smarter decisions by evaluating team strengths, home advantage, and historical performance.

For those looking to dive deeper into NCAAF betting, check out the NCAAF odds page for comprehensive odds and insights. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit from the edge.

Where is the Northwestern Wildcats vs USC Trojans game being played?
Spread (FULL GAME)
EXPECTED VALUECOVER PROB.EXPECTED VALUEBEST LINE
team
NorthwesternSpread
+1.8%
EV
+1.8%
55%
team
USCSpread
-8.4%
EV
-8.4%
47%
MONEYLINE (FULL GAME)
EXPECTED VALUECOVER PROB.EXPECTED VALUEBEST LINE
team
NorthwesternMONEYLINE
+2.3%
EV
+2.3%
20%
team
USCMONEYLINE
-5.8%
EV
-5.8%
80%
Total (FULL GAME)
EXPECTED VALUECOVER PROB.EXPECTED VALUEBEST LINE
over
OVERTotal
+3.6%
EV
+3.6%
56%
under
UNDERTotal
-8.2%
EV
-8.2%
43%
Spread (1H)
BEST LINE
team
NorthwesternSpread
team
USCSpread
MONEYLINE (1H)
BEST LINE
team
NorthwesternMONEYLINE
team
USCMONEYLINE
Total (1H)
BEST LINE
over
OVERTotal
under
UNDERTotal
Spread (2H)
BEST LINE
team
NorthwesternSpread
team
USCSpread
MONEYLINE (2H)
BEST LINE
team
NorthwesternMONEYLINE
team
USCMONEYLINE
Total (2H)
BEST LINE
over
OVERTotal
under
UNDERTotal
Spread (1Q)
BEST LINE
team
NorthwesternSpread
team
USCSpread
MONEYLINE (1Q)
BEST LINE
team
NorthwesternMONEYLINE
team
USCMONEYLINE
Total (1Q)
BEST LINE
over
OVERTotal
under
UNDERTotal
Spread (2Q)
BEST LINE
team
NorthwesternSpread
team
USCSpread
MONEYLINE (2Q)
BEST LINE
team
NorthwesternMONEYLINE
team
USCMONEYLINE
Total (2Q)
BEST LINE
over
OVERTotal
under
UNDERTotal
Spread (3Q)
BEST LINE
team
NorthwesternSpread
team
USCSpread
MONEYLINE (3Q)
BEST LINE
team
NorthwesternMONEYLINE
team
USCMONEYLINE
Total (3Q)
BEST LINE
over
OVERTotal
under
UNDERTotal
Spread (4Q)
BEST LINE
team
NorthwesternSpread
team
USCSpread
MONEYLINE (4Q)
BEST LINE
team
NorthwesternMONEYLINE
team
USCMONEYLINE
Total (4Q)
BEST LINE
over
OVERTotal
under
UNDERTotal
The best odds available today for Northwestern is +14½ -110 at Everygame and for USC -14 -108 at Heritage. The total for the over/under line is o52 -110 at MyBookie.
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