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On September 13, 2025, the Ohio Bobcats will face the Ohio State Buckeyes in a thrilling Saturday football matchup at Ohio Stadium in Columbus, OH, broadcasted on Peacock. With the Buckeyes' strong pass offense averaging 251.5 passing yards per game, they pose a significant challenge to the Bobcats' defense, which allows 215 passing yards on average. Ohio State's defense, however, will need to be wary of Ohio's balanced offensive attack, which boasts 434.5 total yards per game. The point spread favors the Buckeyes at -29, indicating a dominant performance is expected. Bettors should consider Ohio State's strong home record, winning both their games this season, as seen on our NCAAF standings page. Additionally, the Buckeyes' quarterback advantage with their efficient passing game could exploit the Bobcats' defensive weaknesses. For those looking to place a smart bet, Start your OddsTrader Turbo subscription today or place your wager with a U.S. regulated sportsbook.