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The upcoming Saturday football clash on November 1, 2025, between the Ole Miss Rebels and the South Carolina Gamecocks at Vaught-Hemingway Stadium in Oxford, MS, promises a thrilling showdown in the 2025-26 NCAAF season. This game will be broadcast on ESPN, making it accessible to fans and bettors nationwide. Ole Miss comes into this game as the favorite with a point spread of -12.5 and a total points over/under of 55.5, indicating an expectation of a high-scoring affair.
Ole Miss boasts a strong offensive record, averaging 305.5 passing yards and 178.75 rushing yards per game, supported by a solid pass protection line that allows only 1 sack per game. In contrast, South Carolina's defense has been challenged, allowing 194.5 passing yards and 140.625 rushing yards, with a higher sack rate of 2.125 per game, suggesting Ole Miss's passing game could exploit these weaknesses.
South Carolina's offense, led by their starting quarterback, averages 195 passing yards and 107.125 rushing yards, but faces a stout Ole Miss defense that limits opponents to just 199 passing yards and 162.875 rushing yards. The Gamecocks' pass rush, averaging 2.125 sacks per game, could pressure the Ole Miss quarterback, potentially disrupting their rhythm.
Recent form favors Ole Miss, who have secured impressive wins against teams like Oklahoma Sooners (34-26) and LSU Tigers (24-19), while South Carolina has struggled with losses against Alabama (29-22) and Oklahoma (26-7). Ole Miss's ATS record at home is strong at 4-1, making them a reliable pick against the spread. For bettors, the 12.5-point spread and total of 55.5 points provide attractive angles for wagering, especially considering the offensive and defensive matchups.
For a deeper dive into betting trends and game insights, check out our detailed analysis and consider placing your wager with a U.S. regulated sportsbook. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
In their last matchup on October 5, 2024, the Ole Miss Rebels defeated the South Carolina Gamecocks 27-3, showcasing their dominance in this rivalry.