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FINAL
Sep 20, 2025 7:00 PM EDT
SIU 59 vs SEMO 31
Week 4
7-5
Southern Illinois
59
FINAL
31
4-8
Southeast Missouri State
SIU
-5½ (-130)o54½ (-115)
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Southern Illinois Salukis vs Redhawks Odds

Updated:Sep 20, 2025 6:33 AM EDT

The upcoming clash on September 20, 2025, between the Southern Illinois Salukis and Southeast Missouri State Redhawks at Houck Field in Cape Girardeau, MO promises a thrilling encounter in the 2025-26 NCAAF season. As Saturday football brings excitement, fans can catch the action live on ESPN+. The odds are looking interesting with the Salukis and the Redhawks both bringing their A-game to the field. With the current odds slightly favoring the Redhawks, bettors are keeping a keen eye on the point spread. Initially, the odds opened with the Redhawks having a slight edge, but the line has shifted slightly towards a more even matchup, indicating a potential nail-biter.

For those looking to place a smart wager, understanding the movement in betting lines is crucial. The Redhawks, playing at home, are looking to capitalize on their familiar surroundings. Meanwhile, the Salukis are known for their resilience on the road, making this matchup all the more exciting. The best odds available today for the Redhawks is u218 -110 at SugarHouse. To stay updated with the latest movement and make informed betting decisions, check out our NCAAF odds page.

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How have the betting lines moved for the Salukis vs Redhawks game?
Spread (FULL GAME)
EXPECTED VALUECOVER PROB.EXPECTED VALUEBEST LINE
team
Southern IllinoisSpread
-7.5%
EV
-7.5%
47%
team
Southeast Missouri StateSpread
+2.3%
EV
+2.3%
55%
Total (FULL GAME)
EXPECTED VALUECOVER PROB.EXPECTED VALUEBEST LINE
over
OVERTotal
under
UNDERTotal
-5.0%
EV
-5.0%
47%
The best odds available today for Southern Illinois is -4½ -125 at Everygame and for Southeast Missouri State +7½ -123 at Bookmaker. The total for the over/under line is o54½ -110 at MyBookie.
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