Arizona Cardinals vs Cincinnati Bengals Picks

The upcoming NFL showdown on December 28, 2025, between the Arizona Cardinals and Cincinnati Bengals at Paycor Stadium in Cincinnati, OH, is set to be a thrilling Sunday football event. This game promises excitement as both teams battle it out in Week 17 of the 2025-26 NFL season. Fans and bettors alike will be tuning in to Fox for the live broadcast.

Our expert picks and betting tips emphasize a competitive matchup with the Bengals favored by a 7-point spread. Our prediction model suggests a final score of 29-25 in favor of Cincinnati, highlighting the Bengals' edge on the moneyline with a 62.8% confidence and an EV of -13.4%. Meanwhile, the Cardinals hold a 56.3% cover percentage against the spread, indicating a close contest. The projected total score is just under 53.5 points, making the under a smart bet given the model's 50.5% hit rate and an EV of -1.9%.

Reviewing recent performance, our prediction model has been profitable in similar markets, with a strong hit rate on the Cincinnati moneyline and under total bets. These stats provide bettors with valuable insights to make informed wagers. For comprehensive NFL picks and to sharpen your betting strategy, check out our NFL picks and predictions. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.