Betting Trends Cincinnati Bengals vs Buffalo Bills

The upcoming NFL showdown on December 7, 2025, features the Cincinnati Bengals visiting the Buffalo Bills at Highmark Stadium in Orchard Park, NY. This Sunday football game promises to deliver thrilling action and valuable betting trends for sports bettors. The Bills, led by starting quarterback Josh Allen, will look to leverage their potent passing offense against a Bengals defense that allows an average of 256.75 passing yards per game. Buffalo's offense averages 225.33 passing yards and 155.67 rushing yards, while Cincinnati's defense concedes 410 total yards on average, indicating a potential edge for the Bills in offensive production.

Cincinnati's offense, led by Joe Burrow at quarterback, faces a tough Bills defense that ranks high in limiting passing yards and total yards per play. The Bengals average 224.83 passing yards and 88.5 rushing yards per game, challenged by a Bills pass rush that has recorded 14.17 sacks this season. Injuries play a role, with several key players questionable or on injured reserve, including Bills' defensive end Joey Bosa (hamstring) and Bengals' defensive end Trey Hendrickson (hip), who is doubtful for the game. These absences could impact defensive pressure and overall gameplay.

The point spread currently favors the Buffalo Bills by 5.5 points with a total points line of 53.5, suggesting expectations of a moderately high-scoring game. The Bills have a home record of 5-1 and are 6-6 against the spread overall, while the Bengals hold a 2-4 away record and are 5-7 ATS. Recent performances show Buffalo with strong wins and a few losses, while Cincinnati has struggled with more losses but secured a recent 32-14 win over Baltimore. This matchup offers rich betting insights, including a quarterback advantage for the Bills and strong home-field advantage, making Buffalo the best bet to cover the spread.

Fans can catch the game on FOX, and bettors looking to gain an edge can benefit from detailed betting trends and game stats. For those ready to elevate their betting strategy, consider starting an OddsTrader Turbo subscription or place your wager with a trusted U.S. regulated sportsbook. In their last matchup on November 5, 2023, the Cincinnati Bengals defeated the Buffalo Bills 24-18 in Cincinnati, demonstrating that this rivalry can produce competitive and exciting football.