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Jan 4, 2026 4:25 PM EST
Week 18
BUF
-7 (-105)o38 (-110)
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N.Y. Jets vs Buffalo Bills Picks Week 18
Updated:Jan 2, 2026 1:12 AM EST
The upcoming NFL showdown on January 4, 2026, features the N.Y. Jets visiting the Buffalo Bills at Highmark Stadium in Orchard Park, NY. This Week 18 clash promises to be a thrilling conclusion to the regular season as these AFC East rivals battle it out with playoff implications on the line.
Our expert picks favor the Buffalo Bills to win with a predicted score of 21-17, backing the Bills -6.5 point spread. The total points are expected to stay under 39.5, with a predicted total score of about 37.4. The game will be broadcast on CBS, so fans can catch all the action live.
Our prediction model has been profitable in recent games, boasting a strong hit rate on point spreads and totals. In particular, the under 39.5 total has shown good expected value and cover percentage, making it a smart betting tip for this matchup. These stats help bettors make informed decisions and find an edge in their wagers.
For more insights and expert NFL picks, check out our dedicated NFL picks page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
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NFLWeek 18
 Tampa Bay 7-937% -2½ -120Bet365 | |||||||
 San Francisco 12-458% +2 -115SugarHouse | |||||||
 Minnesota 8-857% -7 -121SugarHouse | |||||||
 Houston 11-541% -10 -112BetRivers | |||||||
 Cincinnati 6-1049% -7½ -109Caesars | |||||||
 N.Y. Giants 3-1386% +3½ -110Bet365 | |||||||
 Atlanta 7-958% -3 -121SugarHouse | |||||||
 Jacksonville 12-440% -12½ -115SugarHouse | |||||||
 New England 13-327% -10½ -110Caesars | |||||||
 Las Vegas 2-1462% +6 -115BetRivers | |||||||
 Chicago 11-537% -2½ -121SugarHouse | |||||||
 Buffalo 11-526% -6½ -110Bet365 | |||||||
 Philadelphia 11-562% -3½ -120FanDuel | |||||||
 L.A. Rams 11-58% -7½ -109Caesars | |||||||
 Denver 13-328% -12 -115SugarHouse | |||||||
 Pittsburgh 9-758% +3½ -113Caesars |
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