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Jan 4, 2026 4:25 PM EST
Week 18
BUF
-7 (-110)o38 (-110)
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N.Y. Jets vs Buffalo Bills Picks - NFL Week 18
Updated:Dec 31, 2025 1:22 AM EST
The upcoming NFL game on January 4, 2026, features the N.Y. Jets visiting the Buffalo Bills at Highmark Stadium in Orchard Park, NY. This Sunday football matchup promises an exciting end to the 2025-26 NFL regular season week 18, broadcasted on CBS.
Our picks favor the Buffalo Bills to win with a predicted score of 21 to 17 over the N.Y. Jets. The Bills are favored by a 7.5-point spread, though the Jets have a decent 56.5% coverage percentage on the spread, indicating some value for bettors. The predicted total score is approximately 38, with a slight lean towards the under 39.5 market, which has shown a positive EV and a 50.6% hit rate in recent games.
Our prediction model has been profitable over the last 10 games, especially in the under total market, helping bettors make smart decisions. These stats and trends can guide you in placing informed bets or parlays on this game. For more detailed insights, check out our NFL picks and predictions.
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NFLWeek 18
 Tampa Bay 7-942% -2½ -115Bet365 | |||||||
 San Francisco 12-440% +1½ -110Bet365 | |||||||
 Minnesota 8-856% -5½ -120FanDuel | |||||||
 Houston 11-537% -10 -112BetRivers | |||||||
 Cincinnati 6-1027% -7½ -109Caesars | |||||||
 N.Y. Giants 3-1378% +3½ -110Bet365 | |||||||
 Atlanta 7-955% -3 -114Caesars | |||||||
 Jacksonville 12-433% -12 -115SugarHouse | |||||||
 New England 13-39% -10½ -110Caesars | |||||||
 Las Vegas 2-1433% +6 -117SugarHouse | |||||||
 Chicago 11-533% -2½ -117BetRivers | |||||||
 Buffalo 11-54% -7 -110Bet365 | |||||||
 Philadelphia 11-510% -7 -110Bet365 | |||||||
 L.A. Rams 11-527% -7 -110Bet365 | |||||||
 Denver 13-328% -11½ -110FanDuel | |||||||
 Pittsburgh 9-779% +3½ -113Caesars |
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