New England Patriots vs Cincinnati Bengals Betting Trends

Get ready for an exciting Sunday football clash today as the New England Patriots take on the Cincinnati Bengals at Paycor Stadium in Cincinnati, OH. This NFL Week 12 matchup on November 23, 2025, promises thrilling betting trends and game insights that bettors won’t want to miss. The Patriots come into this game strong with a 9-2 straight-up record and an impressive 8-3 against the spread, while the Bengals are struggling at 3-7 both straight up and ATS. The Patriots are favored by 7.5 points with a total of 50 points on the board, setting the stage for some strategic betting decisions.

New England's quarterback Tommy DeVito is expected to start, while Cincinnati’s starting QB Joe Burrow remains on injured reserve due to a toe injury, sidelining a key offensive threat. This gives the Patriots a clear quarterback advantage. The Patriots’ offense boasts 244 passing yards per game and a solid running game with 53.2 rushing yards, while their defense limits opponents to just 18.7 passing first downs and 18.7 rushing yards allowed per game. The Bengals, on the other hand, average 225.7 passing yards offensively but have been vulnerable defensively, especially without Burrow.

Betting trends highlight New England’s strong road performance and the Bengals’ struggles at home with a 3-7 record ATS. The Patriots’ pass protection and pass rush metrics also show a slight edge over the Bengals, adding to the betting insights. The over/under is set at 50 points, reflecting the potential for a relatively high-scoring game. Injuries to key Bengals defenders like Trey Hendrickson and Cam Sample could tilt the game further in New England’s favor.

For bettors looking to capitalize on these trends, the best spread odds are Cincinnati Bengals +7.5 at -110 and New England Patriots -7.5 at -109, available at Caesars. The over is favored at -112 on the total of 50 points. This game will be broadcast on CBS, providing fans and bettors alike with live coverage of this compelling NFL showdown. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.

Don’t forget to check out their last matchup on September 8, 2024, where New England won 16-10 for additional context and betting perspective. The Patriots have been dominant recently, and their 5-0 away record ATS is a key factor to watch on Sunday football.