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The Monday night football clash on October 20, 2025 between the Tampa Bay Buccaneers vs Detroit Lions at Ford Field in Detroit, MI promises high stakes on ABC/ESPN. Both 2025-26 NFC contenders will look to build momentum as the Lions aim to defend their home turf.
Baker Mayfield leads Tampa Bay’s aerial attack, averaging 244.2 passing yards per game, against Detroit’s defense allowing 212.7. Jared Goff counters with 225 yards through the air versus a Buccaneers unit giving up 231.3. On the ground, Detroit’s 128.7 rush yards per contest meet Tampa Bay’s rush defense yielding just 88.2, while the Bucs average 109.3 rushing yards versus the Lions’ 95.5 allowed.
Detroit’s offensive line allows only 1.5 sacks per game, but faces a Buccaneers pass rush generating 2.7 sacks. Tampa Bay loses Mike Evans (hamstring) and Chris Godwin is doubtful, weakening its receiving corps. Detroit is without Terrion Arnold and Avonte Maddox in the secondary, impacting pass coverage.
The point spread sits at Detroit Lions -5.5 (-107) and Tampa Bay Buccaneers +5.5 (-114) at Caesars, with a total of 53 points (Over -108, Under -113). Detroit is 4-2 SU and 4-2 ATS at home; Tampa Bay is 5-1 SU and 4-2 ATS on the road. Check our NFL standings page for full ATS records. These betting trends and game insights highlight how matchups and injuries inform smart wagering.
In their last matchup on September 15, 2024, the Buccaneers beat the Lions 20-16. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook.
![]() Cincinnati 2-450% +5½ -110Caesars | |||||||
Jacksonville 4-272% +3 -113BetRivers | |||||||
![]() Kansas City 3-330% -11½ -115FanDuel | |||||||
Cleveland 1-550% -3 -105Bet365 | |||||||
![]() Tennessee 1-592% +7 -108BetRivers | |||||||
![]() Chicago 3-239% -5½ -108FanDuel | |||||||
Minnesota 3-276% +2½ -112FanDuel | |||||||
![]() N.Y. Jets 0-664% +1½ -106FanDuel | |||||||
![]() L.A. Chargers 4-267% -1½ -110Bet365 | |||||||
Denver 4-219% -7 -105Bet365 | |||||||
Dallas 2-3-142% +2½ -118BetMGM | |||||||
Arizona 2-489% +6½ -105BetRivers | |||||||
![]() San Francisco 4-253% -1½ -118BetMGM | |||||||
Detroit 4-218% -5½ -106FanDuel | |||||||
Seattle 4-216% -3½ -105BetMGM |
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