San Francisco 49ers vs Philadelphia Eagles Injury Report

The upcoming Sunday night football game on January 11, 2026, features a thrilling NFL matchup between the San Francisco 49ers and the Philadelphia Eagles at Lincoln Financial Field in Philadelphia, PA. This injury report is crucial for bettors looking to make informed decisions as both teams have significant player statuses affecting the game.

The Philadelphia Eagles are facing key injuries with Tackle Lane Johnson out due to a foot injury, and Tight End Dallas Goedert sidelined with a calf issue. Safety Marcus Epps and Outside Linebacker Jaelan Phillips are also out, though Phillips is a limited participant in practice following a concussion. Linebacker Nakobe Dean has just been activated from the reserve/PUP list after a knee injury, which could bolster the Eagles' defense. Defensive Tackle Jalen Carter remains out with a shoulder injury, and Offensive Tackle Cameron Williams has been placed on injured reserve. These absences could impact the Eagles' offensive and defensive lines substantially.

On the other side, the San Francisco 49ers have several players listed as questionable, including Offensive Tackle Trent Williams (knee), Tight End George Kittle (hamstring), Defensive Lineman Keion White (groin), Wide Receiver Ricky Pearsall (knee), and Cornerback Upton Stout (shoulder). Running Back Christian McCaffrey, though questionable due to a calf injury, is expected to play. Fullback Kyle Juszczyk is recovering from a rib injury but participated in limited practice sessions. Defensive Lineman Yetur Gross-Matos will not return from injured reserve, which could affect the 49ers' defensive depth.

This injury report is vital for bettors to consider as it influences team strategies and player performance. Understanding these player injuries and statuses helps in making smarter wagers. The game will be broadcast on Fox, allowing fans to catch all the action live. For more detailed injury updates and to explore betting options, check out the NFL injury list and consider starting your OddsTrader Turbo subscription for an edge in your bets.