St. Louis Cardinals vs San Francisco Giants Picks

The St. Louis Cardinals are set to face the San Francisco Giants on September 24, 2025, at Oracle Park in San Francisco, CA. This MLB clash promises an exciting encounter between two competitive teams. The Cardinals have shown resilience in recent games, particularly with their ability to cover the spread, as seen in their last outing against the Giants where they won 9-8. Our picks for this game suggest betting on St. Louis to cover the +1.5 spread, which has a hit rate of 65.3% and a slightly negative EV of -0.8%. Given the Cardinals' recent performance against the Giants, this seems to be a smart bet.

For those looking to dive deeper into the MLB betting scene, our prediction model has been reasonably successful, especially in the American Total markets. While the prediction for this game is an over 7.5 total, with a predicted total score of approximately 7.70, it's important to note the historical hit rate of 36.6% might suggest some caution. However, the Cardinals' recent form makes them a strong contender for this matchup. Catch the action on fdsmw and consider checking out our MLB picks page for more insights.

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