- LAST 5 GAMES
- LAST 3 VS DETROIT
The upcoming MLB game on May 21, 2026, features the Cleveland Guardians visiting the Detroit Tigers at Comerica Park in Detroit, MI, broadcasted on DSN. Cleveland's left-handed starter Joey Cantillo holds a 3.00 ERA and 1.4444 WHIP, with effective strikeout rates against righties. Detroit's right-handed Casey Mize has a 5.226 ERA and 1.5484 WHIP, showing vulnerability to left-handed batters. The Tigers hold a home record of 13-11, while the Guardians are 14-12 on the road. The moneyline favors Detroit at -113 over Cleveland's +103, with a total points line at 7.5, tilting towards the under. Recent matchups have been low scoring, including a 3-2 Cleveland win in their May 20, 2026 game. Betting trends suggest a close contest with slight edge to Detroit's home advantage and pitching matchup, supported by current injuries affecting Detroit's lineup. These game insights provide a data-driven basis for wagering decisions in this 2026 MLB regular season matchup.
TBC. Legumina (R) 44-3344% -135Bet105 | |||||||
PITB. Chandler (R) 40-4071% +135Everygame | |||||||
SFL. Roupp (R) 33-4659% -123Bookmaker | |||||||
![]() DETT. Melton (R) 34-4667% -108BetAnything | |||||||
WSHC. Cavalli (R) 41-4070% +163Bookmaker | |||||||
![]() TORK. Gausman (R) 39-4119% -144Bet105 | |||||||
NYMF. Peralta (R) 34-4618% -102Bookmaker | |||||||
BOSC. Early (L) 32-4670% +145Everygame | |||||||
STLM. McGreevy (R) 42-3612% -129BetOnline |