New Orleans Pelicans vs Memphis Grizzlies Betting Trends

The upcoming NBA matchup on October 22, 2025, between the New Orleans Pelicans and Memphis Grizzlies at FedExForum in Memphis, TN, promises an exciting basketball showdown. This game is part of the 2025-26 NBA season and will be broadcasted on WVUE. With the Memphis Grizzlies favored by a 4.5-point spread and a total points line set at 237, bettors have intriguing options to consider.

The Memphis Grizzlies have shown strong offensive capabilities recently, scoring 141 points in a win against Miami and 116 points in a loss against Charlotte. New Orleans Pelicans have also been competitive, with close games such as a 132-125 loss to Orlando and a tight 130-128 loss to Houston. Both teams have fluctuated around the total points line, indicating a potentially high-scoring game.

Key players from both teams will be instrumental, with Memphis likely to start their regular lineup and New Orleans expected to field a strong team despite some questionable injury statuses. The Grizzlies average higher points per game and allow fewer points defensively compared to the Pelicans, which could influence the game's pace and outcome.

The 3-point shooting percentages and defensive ratings of both teams suggest a tactical game that could swing either way. The point spread of -4.5 for Memphis and the total points line at 237 are critical betting insights that can guide bettors in making smart wagers. Understanding these betting trends and game insights can give bettors an edge.

For those looking to capitalize on this matchup, the best odds available today for Memphis are -4.5 at Caesars, while New Orleans stands at +4.5. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. For a look back, in their last matchup on March 9, 2025, the Memphis Grizzlies edged out the New Orleans Pelicans 107-104 in a tightly contested game.