Betting Trends Duke Blue Devils vs Michigan State Spartans

The upcoming NCAA basketball game on December 6, 2025, between the Michigan State Spartans and Duke Blue Devils at Jack Breslin Students Events Center in East Lansing, MI, promises an exciting clash. Michigan State, with a strong home record of 7-0, will face off against Duke, who boasts an undefeated 9-0 record overall. Both teams have impressive offensive and defensive stats: Duke averages 89.1 points per game with a 51.2% field goal percentage and 36% from beyond the arc, while Michigan State scores 78.6 points per game with a 47.4% field goal percentage and 33.3% 3-point shooting. Michigan State's defensive rating is 89.85 compared to Duke's 84.39, indicating a tighter defense from Duke.

Key players to watch include Duke's starting five, who consistently score high points and maintain solid assists and rebounds, while Michigan State's starters are known for their strong defensive plays and efficient scoring. Despite Michigan State's solid home advantage, Duke's higher offensive rating (128.35) and better shooting percentages give them an edge. The odds spread and total points are yet to be released, but betting trends suggest Duke might be favored given their dominant recent performances, including a 66-67 win against Florida Gators and an 80-71 loss against Arkansas Razorbacks. Michigan State's recent wins, such as a 71-52 victory over Iowa Hawkeyes, show their competitiveness.

This game will be broadcast on FOX, ensuring fans can catch all the action live. Bettors can use these betting trends and game insights to make informed decisions. The Spartans and Blue Devils have a history of competitive matchups, including their last encounter on November 14, 2023, where Duke won 74-65. Check out the detailed stats and explore the best betting lines to maximize your wagers. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.