Kansas Jayhawks vs Colorado Buffaloes Picks

The upcoming NCAAB matchup on January 21, 2026, features the Kansas Jayhawks visiting the Colorado Buffaloes at the CU Events Center in Boulder, CO. This game is a must-watch for college basketball fans and bettors alike, airing live on ESPN. Our expert picks suggest a competitive clash with Kansas favored to win by a 4.5-point spread, with a predicted final score of 80-75 in favor of Kansas. The Jayhawks have shown strong recent form with profitable betting tips, boasting a solid hit rate in the last 10 games, especially on moneyline bets. Meanwhile, the Buffaloes will be looking to leverage their home court advantage to keep the game close.

Our analysis highlights that the point spread market has been particularly profitable recently, with a high expected value (EV) and a hit rate that bettors can trust. These insights help you make a smart betting decision by focusing on markets where our predictions have consistently outperformed. For more detailed analysis and additional picks, check out our NCAAB picks and predictions page. Don't miss out on placing your bets with confidence ahead of this thrilling college basketball showdown.