Sep 27, 2025 7:00 PM EDT

Week 5

Arizona

4-0

#14 Iowa State

ISU

-6½ (-110)o49½ (-110)

ESPN, 206

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Arizona Wildcats Vs Iowa State Cyclones Odds

Updated:Sep 22, 2025 3:44 AM EDT

As we gear up for an electrifying NCAA Football clash, the Arizona Wildcats are set to take on the Iowa State Cyclones on September 27, 2025, at Jack Trice Stadium in Ames, IA. This Saturday football showdown, broadcasted on ESPN, promises thrilling action with the Cyclones favored by -6 -110. The Wildcats, however, are not to be underestimated, showing a strong +6 -110 on the point spread. Currently, the moneyline odds are +205 for Arizona and -250 for Iowa State, offering intriguing betting opportunities. The total points over/under is set at 49½, indicating a potentially high-scoring affair.

Understanding the odds can significantly enhance your betting strategy. The current spread suggests a competitive matchup, with Iowa State's home advantage potentially tipping the scales. Bettors should note that the best odds for Arizona on the point spread are +6 -110 at Caesars, while Iowa State's -6 -110 is also available at the same sportsbook. If you're eyeing the totals market, the over 49½ -110 line could be appealing given both teams' offensive capabilities.

Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook. For more betting insights and to track odds movements, visit our NCAAF odds page.

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NCAAF

ODDS PICKS PLAYER PROPS FUTURES PLAYER FUTURES INJURIES WEATHER RANKINGS STANDINGS

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NCAAF Thu 09/25

Personalize your notifications and get updates on the teams, players or events you care about most. THU 09/257:30 PM Army 1-2 33% +3½ -110Caesars
East Carolina 2-2 67% -3 -113BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. FRI 09/267:00 PM #8Florida State 3-0 11% -6½ -122FanDuel
Virginia 3-1 89% +7 -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. FRI 09/269:00 PM #24TCU 3-0 20% +2½ -105FanDuel
Arizona State 3-1 80% -2½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. FRI 09/2610:30 PM Houston 3-0 0% -11½ -110FanDuel
Oregon State 0-4 100% +12½ -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/2712:00 PM Bowling Green 2-2 100% +10½ -105FanDuel
Ohio 2-2 0% -10½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/2712:00 PM #22Notre Dame 1-2 25% -5½ -112FanDuel
Arkansas 2-2 75% +6 -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/2712:00 PM Louisville 3-0 33% -3 -115Caesars
Pittsburgh 2-1 67% +3½ -110FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/2712:00 PM Duke 2-2 50% -5½ -110Caesars
Syracuse 3-1 50% +5½ -105FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/2712:00 PM #16Georgia Tech 4-0 0% -14½ -110Caesars
Wake Forest 2-1 100% +15½ -115FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/2712:00 PM Rutgers 3-1 0% +5½ -110FanDuel
Minnesota 2-1 100% -5½ -110FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/2712:00 PM Cincinnati 2-1 83% +6½ -120FanDuel
Kansas 3-1 17% -6 -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/2712:00 PM South Alabama 1-3 100% +13½ -110BetMGM
North Texas 4-0 0% -12½ -115FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/2712:00 PM UCF 3-0 13% +6 -110Caesars
Kansas State 1-3 87% -5½ -115FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/2712:00 PM #21USC 4-0 28% -6½ -110Caesars
#23Illinois 3-1 72% +6½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/2712:45 PM Utah State 3-1 100% +22½ -110Caesars
#18Vanderbilt 4-0 0% -22½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/271:00 PM Eastern Michigan 1-3 100% +6½ -112BetRivers
Central Michigan 2-2 0% -5½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/271:30 PM Georgia Southern 2-2 75% +16½ -110Caesars
James Madison 2-1 25% -15½ -110FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:00 PM Arkansas State 1-3 - +3½ -115FanDuel
Louisiana-Monroe 2-1 - -3 -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM Akron 1-3 - +21½ -115BetMGM
Toledo 2-2 - -20½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM Utah 3-1 0% -10½ -109BetRivers
West Virginia 2-2 100% +11½ -118FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM San Diego State 2-1 0% -3 -105BetMGM
Northern Illinois 1-2 100% +3½ -124FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM California 3-1 60% +6½ -105Caesars
Boston College 1-2 40% -6 -113BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM Connecticut 2-2 - -2½ -114BetRivers
Buffalo 2-2 - +3 -115Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM #11Indiana 4-0 33% -6½ -122FanDuel
Iowa 3-1 67% +7 -105Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM UCLA 0-3 - +6½ -105FanDuel
Northwestern 1-2 - -6½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM Rice 3-1 0% +14½ -110Caesars
Navy 3-0 100% -14½ -108BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM Baylor 2-2 - -19½ -110FanDuel
Oklahoma State 1-2 - +20½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM #4LSU 4-0 71% +1½ -102FanDuel
#13Ole Miss 4-0 29% -1½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM Auburn 3-1 100% +6½ -106FanDuel
#9Texas A&M 3-0 0% -6½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM #1Ohio State 3-0 13% -8½ -108FanDuel
Washington 3-0 87% +9½ -108BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM Lindenwood University 2-2 - -
Miami (OH) 0-3 - -
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/274:00 PM Hawaii 3-2 - +4½ -110Caesars
Air Force 1-2 - -4½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/274:00 PM New Mexico State 2-1 - +14 -110Caesars
New Mexico 2-1 - -13½ -110BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/274:00 PM Tulane 3-1 - -12½ -110FanDuel
Tulsa 2-2 - +13½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/274:15 PM #15Tennessee 3-1 0% -7½ -105Caesars
Mississippi State 4-0 100% +9½ -112BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/276:00 PM Liberty 1-3 0% +15½ -110Caesars
Old Dominion 2-1 100% -15½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/276:00 PM Middle Tennessee 1-3 - +7 -115Caesars
Kennesaw State 2-2 - -6½ -112BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/276:30 PM Rhode Island 4-0 - -
Western Michigan 1-3 - -
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/277:00 PM Memphis 4-0 0% -13½ -110Caesars
Florida Atlantic 1-2 100% +13½ -105FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/277:00 PM Virginia Tech 1-3 100% +10½ -110Caesars
North Carolina State 3-1 0% -10½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/277:00 PM Jacksonville State 2-2 - +3½ -105FanDuel
Southern Miss 2-2 - -3½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/277:00 PM Arizona 3-0 75% +6½ -106FanDuel
#14Iowa State 4-0 25% -6 -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/277:00 PM Western Kentucky 3-1 - -5½ -110Caesars
Missouri State 2-2 - +5½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/277:30 PM Appalachian State 2-1 0% +17½ -110BetMGM
Boise State 2-1 100% -17½ -105Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/277:30 PM San Jose State 1-2 0% +2 -110Caesars
Stanford 1-3 100% -1½ -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/277:30 PM Massachusetts 0-3 - +43½ -110FanDuel
#20Missouri 4-0 - -42½ -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/277:30 PM Washington State 2-2 - +4½ -105FanDuel
Colorado State 1-2 - -4½ -109BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/277:30 PM #6Oregon 4-0 8% +3½ -110Caesars
#3Penn State 3-0 92% -3½ -105FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/277:30 PM #17Alabama 2-1 67% +3½ -120FanDuel
#5Georgia 3-0 33% -3 -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/277:45 PM Kentucky 2-1 67% +6½ -109BetRivers
South Carolina 2-2 33% -6½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/278:00 PM Marshall 2-2 - +2½ -105FanDuel
Louisiana 1-3 - -2½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/279:00 PM Louisiana Tech 3-1 0% -3½ -109BetRivers
UTEP 1-3 100% +4 -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/2710:15 PM #25Brigham Young 3-0 40% -6½ -110Caesars
Colorado 2-2 60% +6½ -110Caesars

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