- Spread
- Money
- Total
- Merged
Personalize your notifications and get updates on the teams, players or events you care about most.
Dec 6, 2025 8:00 PM ESTBig Ten Championship
Week 15
OSU
-5½ (-115)o48½ (-110)
FOXMATCHUP
PREDICTION
ODDS
BOOSTS
PLAYER PROPS
GAME PROPS
INJURIES
WEATHER
CHAT
Event NotificationsStay on top of the action with alerts for game start, scoring, odds updates, predictions and more.
Don't show me this again
Indiana Hoosiers vs Ohio State Buckeyes Picks
Updated:Dec 1, 2025 1:16 AM EST
The upcoming Saturday football game on December 6, 2025, features the Indiana Hoosiers vs Ohio State Buckeyes at Lucas Oil Stadium in Indianapolis, IN. This NCAAF regular season Week 15 clash will be broadcast on Fox, offering fans a thrilling matchup to watch and bet on.
Our expert picks favor the Ohio State Buckeyes to win with a predicted score of 30-21, covering the spread of -5.5. The prediction model has been profitable in recent games, boasting a hit rate of 54.4% on the Over 48.5 total points market, which has a positive EV of 3.1%. This insight supports the expectation of a high-scoring game, making the Over 48.5 total an appealing bet.
Both teams have shown strengths and weaknesses in their recent performances, but Ohio State's consistent winning record in the last 10 games and strong coverage percentage make them the smart bet. Bettors can leverage these statistics to make informed decisions and increase their chances of winning.
For those looking to dive deeper, check out our comprehensive NCAAF picks for more detailed predictions and betting tips. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
UPCOMING GAME PREDICTION
Spread
Money
Total
OSUSpread
CONSENSUS LINE
-5½ (-115)
PROJECTION
IND (21) - OSU (30)
COVER PROBABILITY
EXPECTED VALUE
-2.5%
BET RATING
SEASON COVER %
10/12
83%
OTHER BETS
Sat 12/06 8:00 PMIND @ OSU
Elijah SarrattReceptions
EV
+18.9%
+18.9%
Carnell TateReceptions
EV
+17.5%
+17.5%
Kaelon BlackPlayer to score a touchdown
EV
+17.2%
+17.2%
Jeremiah SmithPlayer Longest Reception
EV
+13.4%
+13.4%
Roman HembyPlayer to score a touchdown
EV
+11.6%
+11.6%
Fernando MendozaPlayer to score a touchdown
EV
+10.1%
+10.1%
Charlie BeckerPlayer to score a touchdown
EV
+8.2%
+8.2%
Brandon InnissPlayer to score a touchdown
EV
+3.2%
+3.2%
CJ DonaldsonPlayer to score a touchdown
EV
+2.1%
+2.1%
Jeremiah SmithReceiving Yards
EV
+1.7%
+1.7%
NCAAF
Spread
Game
- Game
- 1H
- 2H
- 1Q
- 2Q
- 3Q
- 4Q
FBS
Top 25
FBS
FCS
Div. II & III
ACC
BIG-TEN
BIG-12
Pac-12
SEC
Conference USA
Mid-American
Mountain West
Sun Belt
This Week
Last Week
NCAAF Week 15
NCAAF Fri 12/05
 Jacksonville State 8-429% -1½ -103Caesars | |||||||
 James Madison 11-150% -21½ -114FanDuel | |||||||
 #24Tulane 10-254% +2½ -105BetMGM | |||||||
 Boise State 8-4100% -3½ -105Bet365 | |||||||
 #5Texas Tech 11-139% -13 -110Bet365 | |||||||
 Western Michigan 8-425% -2½ -110Bet365 | |||||||
 #10Alabama 10-252% +2½ -104FanDuel | |||||||
 #18Virginia 10-228% -2½ -122FanDuel | |||||||
 #1Ohio State 12-064% -5½ -110Caesars |
Download the app© OddsTrader 2025 All Rights Reserved
The content on this site is for entertainment purposes only. OddsTrader makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event. Please be aware of and respect the laws regarding sports betting for your jurisdiction as they vary from state to state. OddsTrader does not target underaged persons. Using this information to contravene any law or statute is prohibited. This site contains commercial content, and OddsTrader may be compensated for the links provided on this site.Disclosure.
OddsTrader is licensed to operate in NJ, NY, PA, IN, CO, IA, IL, VA, WV, TN, CT, MI, AZ, LA, WY, OR, KS, DC, MA & OH.
Seek help with a gambling addiction at 1-800-Gambler.
OddsTrader uses cookies to help us provide, protect & improve our services. See ourPrivacy Policyfor more details.
ACCEPT & CLOSE