Nov 22, 2025 12:00 PM EST

Week 13

Kansas

6-4

Iowa State

ISU

-3½ (-105)o55½ (-110)

219, FOX Sports 1

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Kansas Jayhawks vs Iowa State Cyclones Betting Trends

Updated:Nov 22, 2025 3:03 AM EST

The upcoming Saturday football game on November 22, 2025, between the Iowa State Cyclones and Kansas Jayhawks at Jack Trice Stadium in Ames, IA, promises an exciting NCAAF regular season Week 13 clash. This matchup offers valuable betting trends and game insights for bettors looking to capitalize on the teams' current form and statistical matchups. The Cyclones, favored by 3.5 points with odds of -107 at Caesars, will host the Jayhawks, who are underdogs at +141 odds. The total points line is set at 55.5 with the under favored at -112.

The Cyclones' starting quarterback is expected to lead their offense, which averages 230.3 passing yards and 164.2 rushing yards per game, showcasing a balanced attack. Iowa State's pass offense, with 230.3 yards, will test Kansas's pass defense that allows 207.5 yards on average. On the ground, Iowa State averages 164.2 rushing yards against Kansas's run defense that yields 169.5 yards per game, suggesting a competitive ground battle. Kansas's offense, led by their quarterback, averages 228.9 passing yards and 159.7 rushing yards, facing a Cyclones defense that allows 222.9 passing yards and 149.7 rushing yards. Pass protection and pass rush stats indicate Iowa State has a slight edge in sacks allowed and sacks made, which could influence quarterback performance and betting outcomes.

Recent game stats show Iowa State with a 6-4 straight-up record and a 4-5-1 against the spread (ATS), while Kansas holds a 5-5 straight-up and 4-6 ATS record. The Cyclones' home performance and ATS records can be explored on our NCAAF standings page. Notably, the last matchup on November 9, 2024, saw Kansas defeat Iowa State 45-36, a high-scoring affair that went over the total points line of 52.5, which bettors should consider.

With the game airing on Fox Sports 1, bettors have a great opportunity to watch the action live. The blend of offensive firepower and defensive resilience from both teams makes this game a compelling betting prospect. For those ready to make smart wagering decisions, Start your OddsTrader Turbo subscription or place your bet with a U.S. regulated sportsbook like Caesars to leverage these betting trends and insights.

Where is the game being played?

ATS Records

Kansas

Iowa State

All

All
1st half
2nd half
1st quarter
2nd quarter
3rd quarter
4th quarter

4-6 (197th)Against the Spread4-5-1 (182nd)

5-5 (135th)Straight Up6-4 (107th)

-4.0Straight Up Units+1.1

5-5Over / Under4-6

TEAM MATCHUP

Kansas

Iowa State

OFF

DEF

OFF

DEF

30.2Points27.1

388.6Total Yards394.5

6.2Yards Per Play5.9

228.9Passing Yards230.3

18.5 - 28.9 (64%)Completions-Attempts18.3 - 30.5 (60%)

7.9Yards Per Passing Play7.6

16.9Sacks-Yards Lost12.9

159.7Rushing Yards164.2

35.8Attempts38

4.5Yards Per Rush4.3

20.51st Downs21.1

10.7Passing10.1

8.7Rushing9.1

1.1Penalties1.9

4.4 / 12.5 (35.2%)3rd Down5.2 / 13.2 (39.4%)

1.6 / 2.5 (64%)4th Down1.3 / 2.1 (61.9%)

3.1 / 3.9 (79.5%)Red Zone3.6 / 4.6 (78.3%)

5.2 (42)Penalties (Yards)4.7 (39.6)

0.4Interceptions0.9

0.5Fumbles Lost0.4

66.5Total Plays70.3

6Kickoffs5.3

1.8Returns0.8

45.2Yards12.8

25.1Yards Per Return16

3.9Punts3.6

2Returns0.8

13.4Yards21

6.7Yards Per Return26.3

HEAD TO HEAD

Kansas

Iowa State

ISU

NCAAF

ODDS PICKS PLAYER PROPS FUTURES PLAYER FUTURES INJURIES WEATHER RANKINGS STANDINGS

Spread

Spread
Money
Total
Merged

Game

Game
1H
2H
1Q
2Q
3Q
4Q

This Week

Last Week

NCAAF Sat 11/22

Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2212:00 PM Rutgers 5-5 69% +31½ -112FanDuel
#1Ohio State 10-0 31% -31 -115BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2212:00 PM Tulsa 3-7 77% +10 -105BetMGM
Army 5-4 23% -9½ -118FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2212:00 PM Delaware 5-5 67% +18 -120BetRivers
Wake Forest 7-3 33% -17½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2212:00 PM #13Miami (FL) 8-2 75% -17½ -114FanDuel
Virginia Tech 3-7 25% +18 -109Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2212:00 PM #22Missouri 7-3 65% +5½ -105BetMGM
#8Oklahoma 8-2 35% -5½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2212:00 PM Louisville 7-3 46% +4 -110Caesars
SMU 7-3 54% -3½ -117SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2212:00 PM Kansas 5-5 66% +3½ -113Caesars
Iowa State 6-4 34% -3½ -105BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2212:00 PM Minnesota 6-4 60% +3½ -105Bet365
Northwestern 5-5 40% -3½ -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2212:00 PM Samford 1-10 - +55½ -110FanDuel
#3Texas A&M 10-0 - -54½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2212:45 PM Charlotte 1-9 37% +44 -110Bet365
#4Georgia 9-1 63% -43½ -112Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/221:00 PM Old Dominion 7-3 44% -10½ -110Bet365
Georgia Southern 5-5 56% +11 -115SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/221:00 PM Washington State 5-5 51% +14 -110BetMGM
James Madison 9-1 49% -13½ -120FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/221:00 PM Baylor 5-5 69% +7 -115Bet365
Arizona 7-3 31% -6½ -114Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/222:00 PM Ball State 4-6 31% +28½ -117Caesars
Toledo 6-4 69% -27½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/222:00 PM Nevada 2-8 74% +7½ -120FanDuel
Wyoming 4-6 26% -6½ -112Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/222:00 PM Missouri State 7-3 79% +6½ -109BetRivers
Kennesaw State 7-3 21% -6½ -105FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/222:00 PM Mercer 9-1 - +27½ -110Bet365
Auburn 4-6 - -27½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/222:00 PM Eastern Illinois 3-8 - +50½ -110FanDuel
#10Alabama 8-2 - -50½ -107Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/222:30 PM Marshall 5-5 27% -4½ -115FanDuel
Appalachian State 4-6 73% +5½ -115Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:00 PM Connecticut 8-3 16% -6½ -110Bet365
Florida Atlantic 4-6 84% +7½ -120FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:00 PM New Mexico State 3-7 76% +3½ -117BetRivers
UTEP 2-8 24% -3 -113Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:00 PM Sam Houston State 2-8 50% +6½ -104Caesars
Middle Tennessee 1-9 50% -6½ -113BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:00 PM Liberty 4-6 76% +2½ -130BetMGM
Louisiana Tech 5-5 24% +1½ -115FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:00 PM South Florida 7-3 27% -21½ -108FanDuel
UAB 3-7 73% +21½ -109Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:30 PM Duke 5-5 29% -6½ -114Caesars
North Carolina 4-6 71% +7 -115BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:30 PM Arkansas 2-8 87% +9 -110Bet365
#17Texas 7-3 13% -8 -115BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:30 PM #15USC 8-2 40% +10½ -112BetRivers
#7Oregon 9-1 60% -10 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:30 PM Michigan State 3-7 41% +17½ -120FanDuel
Iowa 6-4 59% -16½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:30 PM East Carolina 7-3 33% -2½ -110Bet365
UTSA 5-5 67% +2½ -108Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:30 PM Kentucky 5-5 83% +9½ -110Bet365
#14Vanderbilt 8-2 17% -8 -115SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:30 PM Southern Miss 7-3 43% +1½ -115FanDuel
South Alabama 3-7 57% +1½ -115BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:30 PM Jacksonville State 7-3 40% +1½ -112FanDuel
Florida International 5-5 60% -1 -115Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:30 PM Syracuse 3-7 28% +36½ -105BetMGM
#9Notre Dame 8-2 72% -35 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/223:45 PM #24Tulane 8-2 16% -9 -110Bet365
Temple 5-5 84% +9½ -105FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/224:00 PM Oklahoma State 1-9 77% +13½ -115Caesars
UCF 4-6 23% -13 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/224:00 PM #18Michigan 8-2 28% -13½ -120FanDuel
Maryland 4-6 72% +14 -107Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/224:00 PM TCU 6-4 72% +1½ -110Caesars
#23Houston 8-2 28% -1 -113BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/224:00 PM Kansas State 5-5 31% +17½ -112BetRivers
#12Utah 8-2 69% -15½ -125BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/224:00 PM Georgia State 1-9 77% +10½ -110Bet365
Troy 6-4 23% -9½ -118FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/224:15 PM Coastal Carolina 6-4 41% +24 -108Caesars
South Carolina 3-7 59% -23½ -122FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/224:30 PM Furman 6-5 - +42 -110BetRivers
Clemson 5-5 - -41½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/225:00 PM Louisiana-Monroe 3-7 71% +20½ -110FanDuel
Texas State 4-6 29% -19½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/227:00 PM Pittsburgh 7-3 83% +2½ -105BetMGM
#16Georgia Tech 9-1 17% -2½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/227:00 PM Nebraska 7-3 66% +8 -115Bet365
Penn State 4-6 34% -7½ -113BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/227:00 PM Colorado State 2-8 100% +17½ -115BetMGM
Boise State 6-4 0% -16½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/227:00 PM New Mexico 7-3 11% -3½ -102FanDuel
Air Force 3-7 89% +4 -120SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/227:30 PM #20Tennessee 7-3 12% -3½ -118FanDuel
Florida 3-7 88% +4½ -112BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/227:30 PM California 6-4 19% -2½ -120FanDuel
Stanford 3-7 81% +3½ -113Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/227:30 PM #21Illinois 7-3 43% -8 -114BetRivers
Wisconsin 3-7 57% +8½ -110BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/227:30 PM North Texas 9-1 12% -17½ -115BetMGM
Rice 5-5 88% +18½ -115FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/227:45 PM Western Kentucky 8-2 92% +22½ -114FanDuel
LSU 6-4 8% -21½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/228:00 PM #11Brigham Young 9-1 62% -2½ -114FanDuel
Cincinnati 7-3 38% +3 -113Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/228:00 PM #25Arizona State 7-3 15% -7 -110Caesars
Colorado 3-7 85% +7½ -115Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2210:30 PM Washington 7-3 13% -10½ -105FanDuel
UCLA 3-7 87% +10½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2210:30 PM San Jose State 3-7 89% +12½ -110Bet365
San Diego State 8-2 11% -11½ -114FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 11/2210:30 PM Utah State 5-5 83% +2½ -104Caesars
Fresno State 7-3 17% -2½ -115Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. FINALTUE 11/187:00 PM Massachusetts 0-11 14 +34½ -115BetMGM
Ohio 7-4 42 -33½ -115BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. FINALTUE 11/187:00 PM Akron 5-7 19 +3 -114BetRivers
Bowling Green 3-8 16 -2½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. FINALTUE 11/187:00 PM Western Michigan 7-4 35 -6 -115Bet365
Northern Illinois 3-8 19 +7½ -122FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. FINALWED 11/197:00 PM Miami (OH) 6-5 37 -1½ -120BetMGM
Buffalo 5-6 20 +2½ -107Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. FINALWED 11/197:00 PM Central Michigan 7-4 28 -7½ -110Bet365
Kent State 4-7 16 +8½ -115FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. FINALTHU 11/207:30 PM Louisiana 5-6 34 +3 -120BetRivers
Arkansas State 5-6 30 -2½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. FINALFRI 11/218:00 PM Florida State 5-6 11 -6½ -114FanDuel
North Carolina State 6-5 21 +7 -118SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. FINALFRI 11/2110:30 PM Hawaii 7-4 10 +2½ -105BetMGM
UNLV 9-2 38 -2 -121SugarHouse

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Kansas Jayhawks vs Iowa State Cyclones Betting Trends

ATS Records

Kansas

Iowa State

TEAM MATCHUP

Kansas

Iowa State

Recent Results

Kansas

Iowa State

HEAD TO HEAD

Kansas

Iowa State

Kansas

UPCOMING SCHEDULE

Iowa State