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The upcoming Saturday football clash on November 29, 2025, between the Kentucky Wildcats and Louisville Cardinals at L&N Federal Credit Union Stadium in Louisville, KY, promises an exciting showdown in the 2025-26 NCAAF season. This game will be broadcast on ESPN Networks and ACC Network, making it accessible for fans and bettors nationwide.
Our picks and betting tips favor Louisville to edge out Kentucky with a predicted score of 26-23. The Cardinals are favored by 3.5 points, but our model indicates a strong cover potential for Kentucky with the +3.5 spread, which has a 55.5% hit rate and an EV of 3.1%. This insight reflects our model's profitable trend in the point spread market over the last 10 games, helping bettors make smarter decisions.
Both teams have shown competitive form, with Louisville recently winning 6 of their last 10 games in the point spread market and Kentucky showing potential with key wins. Bettors can leverage these stats to find value bets and parlays for this high-stakes rivalry game. For more expert analysis and comprehensive NCAAF picks, visit our NCAAF picks page.
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![]() Massachusetts 0-1180% +14½ -110Bet365 | |||||||
Eastern Michigan 4-767% +6½ -110Bet365 | |||||||
![]() Memphis 8-320% -5½ -107Caesars | |||||||
Buffalo 5-650% +6½ -110BetMGM | |||||||
![]() Mississippi State 5-688% +7½ -110BetMGM | |||||||
Nebraska 7-489% +5½ -110BetMGM | |||||||
![]() Northern Illinois 3-8- -4½ -112FanDuel | |||||||
![]() Kansas 5-660% +13½ -106FanDuel | |||||||
![]() Colorado State 2-90% +3½ -120FanDuel | |||||||
![]() #16Georgia Tech 9-275% +13 -105BetMGM | |||||||
![]() New Mexico 8-3100% +2½ -115FanDuel | |||||||
![]() North Texas 10-120% -19½ -110Bet365 | |||||||
![]() Utah State 6-5100% +3½ -122FanDuel | |||||||
![]() #17Texas 8-371% +2½ -104FanDuel | |||||||
![]() Purdue 2-980% +28½ -110BetMGM | |||||||
![]() #25Arizona State 8-336% +1½ -110Caesars | |||||||
West Virginia 4-7100% +21½ -122FanDuel | |||||||
![]() Florida Atlantic 4-775% +6½ -110Bet365 | |||||||
Louisville 7-40% -3½ -105FanDuel | |||||||
![]() South Carolina 3-760% -2 -110Bet365 | |||||||
![]() #18Michigan 9-275% +10½ -115FanDuel | |||||||
![]() Pittsburgh 8-333% +6½ -102FanDuel | |||||||
Central Michigan 7-450% +10½ -110BetMGM | |||||||
Miami (OH) 6-5- -17½ -110Bet365 | |||||||
![]() Kansas State 5-633% -17 -110Bet365 | |||||||
Baylor 5-667% -2 -113BetRivers | |||||||
Oklahoma State 1-10- +14 -110BetMGM | |||||||
![]() Delaware 5-60% -5 -110Bet365 | |||||||
![]() Sam Houston State 2-9- +10½ -110FanDuel | |||||||
#11Brigham Young 10-10% -17½ -110Bet365 | |||||||
Marshall 5-60% -7 -110Bet365 | |||||||
![]() Old Dominion 8-3100% -26½ -110BetMGM | |||||||
![]() Missouri State 7-450% -3 -110Bet365 | |||||||
![]() Jacksonville State 7-40% +2½ -110Caesars | |||||||
Appalachian State 5-6100% -2½ -109Caesars | |||||||
Syracuse 3-8- +3½ -122FanDuel | |||||||
![]() Tulsa 4-70% -8½ -110Bet365 | |||||||
Texas State 5-60% -7½ -115FanDuel | |||||||
![]() Louisiana 5-6- -11½ -109Caesars | |||||||
New Mexico State 4-7- -4½ -110Bet365 | |||||||
#20Tennessee 8-327% -2 -114BetRivers | |||||||
![]() Duke 6-5100% -2½ -110Bet365 | |||||||
Rutgers 5-6100% +11½ -110BetRivers | |||||||
![]() #8Oklahoma 9-221% -10 -107Caesars | |||||||
![]() UTSA 6-533% -6½ -110BetMGM | |||||||
TCU 6-40% -4 -110Bet365 | |||||||
Southern Miss 7-467% -6½ -120FanDuel | |||||||
![]() Arkansas 2-9100% +2½ -104FanDuel | |||||||
Minnesota 6-50% -1½ -107Caesars | |||||||
![]() Washington 8-374% +7 -110BetMGM | |||||||
![]() Liberty 4-750% +2½ -105FanDuel | |||||||
![]() Coastal Carolina 6-5100% +22½ -110Bet365 | |||||||
Florida 3-80% -2 -105Bet365 | |||||||
![]() Washington State 5-633% -13½ -110Bet365 | |||||||
![]() South Florida 8-30% -25½ -110BetMGM | |||||||
Michigan State 3-850% -3½ -110BetRivers | |||||||
![]() #19Virginia 9-233% -10½ -110Bet365 | |||||||
![]() North Carolina State 6-533% -7 -110Bet365 | |||||||
Auburn 5-6100% +5½ -110Caesars | |||||||
#24Tulane 9-2- -29 -109BetRivers | |||||||
#21Illinois 7-40% -6½ -113BetRivers | |||||||
#15USC 8-2100% -20½ -110Bet365 | |||||||
![]() California 6-5100% +12½ -109Caesars | |||||||
![]() Nevada 3-8100% +8½ -110Bet365 | |||||||
![]() San Jose State 3-8100% +2½ -108FanDuel | |||||||
Stanford 4-7100% +32½ -108Caesars | |||||||
![]() Hawaii 7-40% -10 -110Bet365 |
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