Sep 27, 2025 12:00 PM EDT

Week 5

Louisville

2-1

Pittsburgh

LOU

-4½ (-110)o57½ (-110)

ESPN2, 209, ESPN Networks

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Louisville Cardinals vs Pittsburgh Panthers Weather

Updated:Sep 26, 2025 7:15 AM EDT

The highly anticipated matchup between the Louisville Cardinals and the Pittsburgh Panthers is set to take place on September 27, 2025, at Acrisure Stadium in Pittsburgh, PA. With the Panthers playing at home, they are looking to capitalize on their strong home record. Historically, Pittsburgh has shown resilience in inclement weather, often turning challenging conditions to their advantage. This confidence stems from their experience in varied weather conditions, including rain and cold, which don't seem to faze them. The weather forecast for the game predicts partially cloudy skies with temperatures ranging from 71 to 74.9°F and a gentle breeze from the east. These conditions are ideal for a game of football and should not adversely affect play. The Louisville Cardinals, known for their adaptability, will be looking to upset the Panthers' home advantage. This game is a part of the NCAAF league and will be broadcasted on ESPN2, providing fans with an exciting Saturday football experience. For bettors, understanding how the weather could influence gameplay is crucial. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. Check out the NCAAF weather conditions for more insights.

How do the Pittsburgh Panthers perform in bad weather?

NCAAF

ODDS PICKS PLAYER PROPS FUTURES PLAYER FUTURES INJURIES WEATHER RANKINGS STANDINGS

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This Week

Last Week

NCAAF Fri 09/26

Personalize your notifications and get updates on the teams, players or events you care about most. FRI 09/267:00 PM #8Florida State 3-0 24% -6½ -121BetRivers
Virginia 3-1 76% +7 -115Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. FRI 09/269:00 PM #24TCU 3-0 37% +3 -110Caesars
Arizona State 3-1 63% -2½ -122SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. FRI 09/2610:30 PM Houston 3-0 20% -13 -113BetRivers
Oregon State 0-4 80% +13½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/2712:00 PM Bowling Green 2-2 74% +8½ -115FanDuel
Ohio 2-2 26% -7½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/2712:00 PM #22Notre Dame 1-2 41% -4½ -105BetMGM
Arkansas 2-2 59% +4½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/2712:00 PM Louisville 3-0 36% -4 -113Caesars
Pittsburgh 2-1 64% +5 -117BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/2712:00 PM Duke 2-2 84% -4 -110Bet365
Syracuse 3-1 16% +5½ -115SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/2712:00 PM #16Georgia Tech 4-0 31% -13½ -120FanDuel
Wake Forest 2-1 69% +14 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/2712:00 PM Rutgers 3-1 38% +5½ -112FanDuel
Minnesota 2-1 62% -4½ -114SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/2712:00 PM Cincinnati 2-1 81% +5½ -120BetMGM
Kansas 3-1 19% -4½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/2712:00 PM South Alabama 1-3 88% +13½ -110BetMGM
North Texas 4-0 12% -12½ -110FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/2712:00 PM UCF 3-0 30% +6½ -115FanDuel
Kansas State 1-3 70% -5½ -113SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/2712:00 PM #21USC 4-0 17% -6½ -114FanDuel
#23Illinois 3-1 83% +7 -115Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/2712:45 PM Utah State 3-1 81% +23½ -113BetRivers
#18Vanderbilt 4-0 19% -22½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/271:00 PM Eastern Michigan 1-3 57% +5 -109BetRivers
Central Michigan 2-2 43% -4½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/271:30 PM Georgia Southern 2-2 72% +17½ -112BetRivers
James Madison 2-1 28% -17 -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:00 PM Arkansas State 1-3 19% +1½ -110Bet365
Louisiana-Monroe 2-1 81% -1 -112BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM Akron 1-3 82% +21 -112BetRivers
Toledo 2-2 18% -20½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM Utah 3-1 5% -12½ -110Caesars
West Virginia 2-2 95% +12½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM San Diego State 2-1 16% -2½ -105Caesars
Northern Illinois 1-2 84% +2½ -105BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM California 3-1 41% +6½ -110BetMGM
Boston College 1-2 59% -6½ -105Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM Connecticut 2-2 11% -3½ -105Caesars
Buffalo 2-2 89% +4 -113BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM #11Indiana 4-0 24% -7½ -110BetMGM
Iowa 3-1 76% +8½ -115BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM UCLA 0-3 35% +6½ -110Caesars
Northwestern 1-2 65% -6 -114SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM Rice 3-1 44% +14½ -117Caesars
Navy 3-0 56% -14 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM Baylor 2-2 29% -20½ -115BetMGM
Oklahoma State 1-2 71% +21 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM #4LSU 4-0 49% +1½ -105Bet365
#13Ole Miss 4-0 51% -1 -115SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM Auburn 3-1 57% +6½ -109BetRivers
#9Texas A&M 3-0 43% -6½ -105BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM #1Ohio State 3-0 20% -8 -110Caesars
Washington 3-0 80% +8½ -114SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/273:30 PM Lindenwood University 2-2 - +20½ -110FanDuel
Miami (OH) 0-3 - -20½ -110FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/274:00 PM Hawaii 3-2 74% +6½ -105BetMGM
Air Force 1-2 26% -6½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/274:00 PM New Mexico State 2-1 80% +14½ -105FanDuel
New Mexico 2-1 20% -14½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/274:00 PM Tulane 3-1 43% -14½ -118FanDuel
Tulsa 2-2 57% +16 -115SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/274:15 PM #15Tennessee 3-1 18% -7½ -105FanDuel
Mississippi State 4-0 82% +8½ -115BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/276:00 PM Liberty 1-3 60% +15½ -118FanDuel
Old Dominion 2-1 40% -14½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/276:00 PM Middle Tennessee 1-3 43% +7½ -110Bet365
Kennesaw State 2-2 57% -7½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/276:30 PM Rhode Island 4-0 - +7½ -110FanDuel
Western Michigan 1-3 - -7½ -110FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/277:00 PM Memphis 4-0 11% -13½ -118FanDuel
Florida Atlantic 1-2 89% +14 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/277:00 PM Virginia Tech 1-3 65% +11 -110BetRivers
North Carolina State 3-1 35% -10½ -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/277:00 PM Jacksonville State 2-2 82% +4 -110Bet365
Southern Miss 2-2 18% -3½ -114BetRivers
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/277:00 PM Arizona 3-0 72% +6½ -110BetMGM
#14Iowa State 4-0 28% -6 -105Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/277:00 PM Western Kentucky 3-1 40% -3½ -115FanDuel
Missouri State 2-2 60% +5 -115SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/277:30 PM Appalachian State 2-1 60% +16½ -110BetMGM
Boise State 2-1 40% -15½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/277:30 PM San Jose State 1-2 81% +3½ -112FanDuel
Stanford 1-3 19% -3 -115BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/277:30 PM Massachusetts 0-3 89% +45 -105Bet365
#20Missouri 4-0 11% -44½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/277:30 PM Washington State 2-2 80% +5½ -110Caesars
Colorado State 1-2 20% -5 -114SugarHouse
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/277:30 PM #6Oregon 4-0 25% +3½ -108FanDuel
#3Penn State 3-0 75% -3½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/277:30 PM #17Alabama 2-1 67% +3 -108BetRivers
#5Georgia 3-0 33% -2½ -124FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/277:45 PM Kentucky 2-1 82% +6 -112BetRivers
South Carolina 2-2 18% -5½ -108FanDuel
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/278:00 PM Marshall 2-2 40% +1½ -120FanDuel
Louisiana 1-3 60% +1 -120BetMGM
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/279:00 PM Louisiana Tech 3-1 19% -3½ -105BetMGM
UTEP 1-3 81% +3½ -110Caesars
Personalize your notifications and get updates on the teams, players or events you care about most. SAT 09/2710:15 PM #25Brigham Young 3-0 22% -6½ -122FanDuel
Colorado 2-2 78% +7 -110Bet365
Personalize your notifications and get updates on the teams, players or events you care about most. FINALTHU 09/257:30 PM Army 1-3 6 +3½ -105BetMGM
East Carolina 3-2 28 -3 -118BetRivers

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