Louisville Cardinals vs SMU Mustangs Player Props

The upcoming showdown on November 22, 2025, between the Louisville Cardinals and SMU Mustangs at Gerald J. Ford Stadium in Dallas, TX, is set to be a thrilling NCAAF regular season Week 13 game. Fans and bettors alike will want to focus on the player props for this matchup, as both teams bring contrasting strengths to the field.

Louisville's passing offense, led by Miller Moss, faces a tough SMU pass defense. Our projections suggest Moss will go under 229.5 passing yards with a 64.9% hit rate and an 11.7% positive EV, making this a strong prop bet to consider. SMU's Kevin Jennings also looks promising under 270.5 passing yards with a 65.1% hit rate and 11.6% EV. The run game battle is intriguing; Louisville's Keyjuan Brown is projected under 87.5 rushing yards, while SMU's TJ Harden hovers around the 53.5 rushing yards mark with nearly balanced over/under hit rates. These rushing yards props provide great insights into how the pace of play might influence the game.

Our prop bet results over the last 10 games have shown a solid track record, especially in passing yards and rushing yards markets, delivering consistent value for bettors. With the game airing on ESPN2, viewers have a perfect opportunity to watch and wager simultaneously. Don’t miss out on expert player projections and detailed prop bets that can help you make smarter decisions. Check out the full NCAAF player props on our league props page and enhance your betting strategy today. Ready to bet smarter? Start your OddsTrader Turbo subscription or place your bet with a U.S. regulated sportsbook to gain the edge.