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The upcoming NCAAF clash on November 22, 2025, between the Western Kentucky Hilltoppers and LSU Tigers at Tiger Stadium in Baton Rouge, LA, promises an exciting Saturday football showdown. Fans can catch all the action live on SEC Network and ESPN Networks, making it a must-watch event.
Current odds favor the home team, LSU Tigers, as the favorites with a point spread of -22 -109 at Caesars sportsbook, compared to the Western Kentucky Hilltoppers at +22 -110. The opening odds showed a similar spread but with slightly different pricing, indicating steady confidence in LSU maintaining their edge. Bettors should note the total points over/under is set at 50.5, with the over at -113 and the under at -108, providing a balanced market for total points scored.
Understanding these odds and betting lines is crucial for making informed wagers. The significant point spread suggests LSU is expected to dominate, but Western Kentucky could provide value as the underdog. By analyzing the odds movement and current betting trends, bettors can identify smart opportunities to place their bets.
For a deeper dive into NCAAF odds and more betting insights, visit our NCAAF odds page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
![]() #1Ohio State 10-031% -31 -115BetRivers | |||||||
Army 5-423% -9½ -120FanDuel | |||||||
![]() Wake Forest 7-333% -17½ -110Caesars | |||||||
Virginia Tech 3-725% +18 -109Caesars | |||||||
![]() #8Oklahoma 8-235% -5½ -110Bet365 | |||||||
SMU 7-354% -3½ -117SugarHouse | |||||||
![]() Iowa State 6-434% -3½ -105BetMGM | |||||||
![]() Northwestern 5-540% -3½ -110BetMGM | |||||||
#3Texas A&M 10-0- -54½ -110Bet365 | |||||||
![]() #4Georgia 9-163% -43½ -112Caesars | |||||||
![]() Georgia Southern 5-556% +11 -115SugarHouse | |||||||
![]() James Madison 9-149% -13½ -120FanDuel | |||||||
![]() Arizona 7-331% -6½ -114Caesars | |||||||
![]() Toledo 6-469% -27½ -110Bet365 | |||||||
Wyoming 4-626% -6½ -112Caesars | |||||||
![]() Kennesaw State 7-321% -6½ -105FanDuel | |||||||
Auburn 4-6- -27½ -110Bet365 | |||||||
#10Alabama 8-2- -50½ -107Caesars | |||||||
Appalachian State 4-673% +5½ -115Caesars | |||||||
![]() Florida Atlantic 4-684% +7½ -120FanDuel | |||||||
![]() UTEP 2-824% -3 -113Caesars | |||||||
![]() Middle Tennessee 1-950% -6½ -113BetRivers | |||||||
![]() Louisiana Tech 5-524% +1½ -115FanDuel | |||||||
UAB 3-773% +21½ -109Caesars | |||||||
![]() North Carolina 4-671% +7 -115BetMGM | |||||||
![]() #17Texas 7-313% -8 -115BetRivers | |||||||
![]() #7Oregon 9-160% -10 -110Bet365 | |||||||
Iowa 6-459% -16½ -110Bet365 | |||||||
![]() UTSA 5-567% +2½ -108Caesars | |||||||
![]() #14Vanderbilt 8-217% -8 -115SugarHouse | |||||||
![]() South Alabama 3-757% +1½ -115BetMGM | |||||||
![]() Florida International 5-560% -1 -115Bet365 | |||||||
#9Notre Dame 8-272% -35 -110Bet365 | |||||||
Temple 5-584% +9½ -105FanDuel | |||||||
UCF 4-623% -13 -110Bet365 | |||||||
Maryland 4-672% +14 -107Caesars | |||||||
![]() #23Houston 8-228% -1 -113BetRivers | |||||||
![]() #12Utah 8-269% -15½ -125BetMGM | |||||||
Troy 6-423% -9½ -118FanDuel | |||||||
![]() South Carolina 3-759% -23½ -122FanDuel | |||||||
![]() Clemson 5-5- -41½ -110Caesars | |||||||
Texas State 4-629% -19½ -110Bet365 | |||||||
![]() #16Georgia Tech 9-117% -2½ -110Bet365 | |||||||
![]() Penn State 4-634% -7½ -113BetRivers | |||||||
![]() Boise State 6-40% -16½ -110Bet365 | |||||||
Air Force 3-789% +4 -120SugarHouse | |||||||
Florida 3-788% +4½ -112BetRivers | |||||||
Stanford 3-781% +3½ -113Caesars | |||||||
![]() Wisconsin 3-757% +8½ -110BetMGM | |||||||
Rice 5-588% +18½ -115FanDuel | |||||||
LSU 6-48% -21½ -110Bet365 | |||||||
![]() Cincinnati 7-338% +3 -113Caesars | |||||||
![]() Colorado 3-785% +7½ -115Bet365 | |||||||
UCLA 3-787% +10½ -110Bet365 | |||||||
San Diego State 8-211% -11½ -114FanDuel | |||||||
![]() Fresno State 7-317% -2½ -115Bet365 | |||||||
![]() Ohio 7-442 -33½ -115BetRivers | |||||||
Bowling Green 3-816 -2½ -110Bet365 | |||||||
![]() Northern Illinois 3-819 +7½ -122FanDuel | |||||||
Buffalo 5-620 +2½ -107Caesars | |||||||
![]() Kent State 4-716 +8½ -115FanDuel | |||||||
Arkansas State 5-630 -2½ -110Bet365 | |||||||
![]() North Carolina State 6-521 +7 -118SugarHouse | |||||||
UNLV 9-238 -2 -121SugarHouse |
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