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The upcoming clash on November 22, 2025, between the Missouri Tigers and Oklahoma Sooners at Gaylord Family Oklahoma Memorial Stadium in Norman, OK, promises thrilling Saturday football action in the NCAAF league. This highly anticipated game offers bettors a prime opportunity to capitalize on expert picks and betting tips tailored for this matchup.
Our prediction model favors the Oklahoma Sooners to win with a predicted score of 25 to 20 against the Missouri Tigers, covering the spread at -7.5. The total points are expected to go over 42.5, with a predicted total score around 45. Oklahoma's recent performance shows a strong 64.8% coverage in the 2-way market and a favorable -10.2% EV, indicating value in betting on the Sooners. Meanwhile, Missouri holds a 54.7% coverage on the point spread, suggesting competitive action on both sides.
In the last 10 games, our prediction model has been profitable, boasting a hit rate of about 55% on the American totals market. This strong track record helps bettors make informed decisions, increasing their chances of success. The game will be broadcast on ABC and ESPN networks, making it easy for fans to tune in and follow the action live.
For those looking to dive deeper into the NCAAF season and explore more expert picks, check out our comprehensive NCAAF picks page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
![]() Ohio 6-423% -33 -110Bet365 | |||||||
Bowling Green 3-748% -2½ -118FanDuel | |||||||
![]() Northern Illinois 3-757% +7 -117BetRivers | |||||||
Buffalo 5-550% +1½ -110Bet365 | |||||||
![]() Kent State 4-681% +9½ -105Bet365 | |||||||
Arkansas State 5-50% -2½ -117Caesars | |||||||
![]() North Carolina State 5-564% +5 -118BetRivers | |||||||
UNLV 8-211% -2½ -110FanDuel | |||||||
![]() #1Ohio State 10-040% -30½ -114FanDuel | |||||||
Army 5-450% -9½ -120FanDuel | |||||||
![]() Wake Forest 7-318% -17 -109BetRivers | |||||||
Virginia Tech 3-775% +18 -117SugarHouse | |||||||
![]() #11Oklahoma 8-236% -7½ -105BetMGM | |||||||
SMU 7-313% -2½ -124FanDuel | |||||||
![]() Iowa State 6-40% -4 -114BetRivers | |||||||
![]() Northwestern 5-50% -3½ -110Bet365 | |||||||
#3Texas A&M 10-0- - | |||||||
![]() #5Georgia 9-155% -43½ -115FanDuel | |||||||
![]() Georgia Southern 5-567% +12½ -110Bet365 | |||||||
![]() James Madison 9-122% -12½ -115FanDuel | |||||||
![]() Arizona 7-314% -6½ -110Bet365 | |||||||
![]() Toledo 6-450% -27 -110BetRivers | |||||||
Wyoming 4-60% -6½ -110Bet365 | |||||||
![]() Kennesaw State 7-317% -6½ -105FanDuel | |||||||
#4Alabama 8-2- - | |||||||
Auburn 4-6- - | |||||||
Appalachian State 4-686% +4½ -109Caesars | |||||||
![]() Florida Atlantic 4-683% +7½ -115Bet365 | |||||||
![]() UTEP 2-840% -3 -110Bet365 | |||||||
![]() Middle Tennessee 1-917% -6½ -115BetMGM | |||||||
![]() Louisiana Tech 5-50% +1½ -118FanDuel | |||||||
UAB 3-775% +21½ -109Caesars | |||||||
![]() North Carolina 4-689% +7 -114BetRivers | |||||||
![]() #10Texas 7-310% -8½ -110FanDuel | |||||||
![]() #8Oregon 9-141% -9½ -115BetMGM | |||||||
#21Iowa 6-422% -16½ -110Bet365 | |||||||
![]() UTSA 5-5100% +2½ -105BetMGM | |||||||
![]() #14Vanderbilt 8-218% -8½ -118SugarHouse | |||||||
![]() South Alabama 3-7100% +2½ -110FanDuel | |||||||
![]() Florida International 5-50% +1½ -120BetMGM | |||||||
#9Notre Dame 8-233% -35 -110Bet365 | |||||||
Temple 5-587% +8½ -113BetRivers | |||||||
UCF 4-640% -14 -105BetMGM | |||||||
Maryland 4-6100% +13½ -105BetMGM | |||||||
![]() Houston 8-20% -1 -114BetRivers | |||||||
![]() #13Utah 8-210% -17 -120Bet365 | |||||||
Troy 6-433% -11 -110Bet365 | |||||||
![]() South Carolina 3-725% -23½ -110FanDuel | |||||||
![]() Clemson 5-5- - | |||||||
Texas State 4-6- -17½ -110Bet365 | |||||||
![]() #16Georgia Tech 9-16% -2½ -110Bet365 | |||||||
![]() Penn State 4-625% -9½ -110Caesars | |||||||
![]() Boise State 6-40% -16½ -110Bet365 | |||||||
Air Force 3-7100% +3½ -114Caesars | |||||||
Florida 3-782% +5 -120BetRivers | |||||||
Stanford 3-791% +3 -109Caesars | |||||||
![]() Wisconsin 3-7100% +8½ -105FanDuel | |||||||
Rice 5-560% +18½ -110Bet365 | |||||||
LSU 6-433% -21½ -110Bet365 | |||||||
![]() #25Cincinnati 7-395% +2½ -106FanDuel | |||||||
![]() Colorado 3-789% +7½ -115Bet365 | |||||||
UCLA 3-775% +10½ -108Caesars | |||||||
San Diego State 8-20% -11½ -110BetMGM | |||||||
![]() Fresno State 7-30% -2½ -114BetRivers |
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