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As we gear up for Saturday football on September 20, 2025, the South Carolina Gamecocks are set to face off against the Missouri Tigers at Memorial Stadium/Faurot Field in Columbia, MO. Broadcast live on ESPN, this NCAAF clash between two competitive teams promises to be a thrilling showdown. Missouri, coming in strong with a 3-0 record, has shown prowess in both offensive and defensive plays. The Tigers' passing offense, averaging 284.7 yards per game, might give them the edge over South Carolina's defense, which has had some struggles. Meanwhile, South Carolina, with a 2-1 record, is looking to bounce back from their recent defeat against Vanderbilt. The Gamecocks will need to tighten their defense, especially against the run, to stand a chance against Missouri's aggressive rushing game.
Quarterback performances will be crucial in this matchup. Missouri's starter has been efficient, contributing to their high scoring games, while South Carolina's quarterback will need to step up to counter. The spread odds favor Missouri at -10.5, with a total points line set at 48.0, indicating expectations of a high-scoring game. Bettors should consider Missouri's strong home record and South Carolina's challenges on the road when placing their bets. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
In their last matchup on November 16, 2024, the Gamecocks edged out the Tigers 34-30, a result that might inspire them this Saturday. Check out our NCAAF standings page for more insights.
 Oklahoma State 1-117% u54½ -110Caesars | |||||||
 Rutgers 3-054% u45½ -106FanDuel | |||||||
 Army 1-136% u51½ -115FanDuel | |||||||
 TCU 2-017% u63½ -110FanDuel | |||||||
 Miami (OH) 0-227% u50½ -114BetRivers | |||||||
 Louisville 2-017% u51½ -110Bet365 | |||||||
 Clemson 1-224% u54½ -109BetRivers | |||||||
 Wisconsin 2-144% u44½ -115BetMGM | |||||||
 #16Utah 3-05% u56½ -105BetMGM | |||||||
 Memphis 3-025% u61 -109BetRivers | |||||||
 South Florida 2-1- u56½ -110Bet365 | |||||||
 Virginia Tech 0-3- u48½ -110Bet365 | |||||||
 #15Tennessee 2-140% u69½ -110BetMGM | |||||||
 Central Michigan 1-2- u45½ -110Bet365 | |||||||
 #6Oregon 3-06% u56½ -110Bet365 | |||||||
 Eastern Michigan 0-358% u50½ -105BetMGM | |||||||
 UCF 2-025% u46½ -109Caesars | |||||||
 #7Florida State 2-018% u55½ -110Caesars | |||||||
 Western Michigan 0-338% u50½ -105BetMGM | |||||||
 Buffalo 2-10% u44½ -114Caesars | |||||||
 #11Oklahoma 3-04% u47 -110BetRivers | |||||||
 #13Ole Miss 3-016% u62 -113BetRivers | |||||||
 Connecticut 1-225% u53½ -110Caesars | |||||||
 Nebraska 3-026% u47½ -110Caesars | |||||||
 #24Notre Dame 0-29% u52½ -115BetMGM | |||||||
 Liberty 1-20% u47 -109BetRivers | |||||||
 Ohio 1-2- u51½ -110Bet365 | |||||||
 Duke 1-236% u57½ -115FanDuel | |||||||
 Mississippi State 3-00% u49½ -115BetMGM | |||||||
 #18Georgia Tech 3-011% u53½ -118BetMGM | |||||||
 San Jose State 0-2- u50½ -110Bet365 | |||||||
 Kansas 2-10% u54½ -105BetMGM | |||||||
 Kennesaw State 1-280% u57½ -110Caesars | |||||||
 Florida International 2-136% u55½ -109BetRivers | |||||||
 Akron 0-3- u51½ -108FanDuel | |||||||
 South Alabama 1-233% u51½ -110Caesars | |||||||
 #23Missouri 3-00% u48½ -105BetMGM | |||||||
 Western Kentucky 2-10% u54 -110Caesars | |||||||
 Air Force 1-175% u52 -113BetRivers | |||||||
 Middle Tennessee 1-2100% u47½ -110Caesars | |||||||
 Jacksonville State 1-2- u60½ -110Bet365 | |||||||
 Georgia Southern 1-2- u55½ -110Bet365 | |||||||
 Missouri State 1-2- u52½ -110Bet365 | |||||||
 East Carolina 2-10% u50 -110BetRivers | |||||||
 #4Miami (FL) 3-037% u51½ -113BetRivers | |||||||
 #19Indiana 3-07% u53 -114BetRivers | |||||||
 Baylor 2-110% u61 -112BetRivers | |||||||
 Virginia 2-167% u48½ -110Caesars | |||||||
 Louisiana Tech 2-162% u51 -112BetRivers | |||||||
 Washington State 2-10% u52½ -110Bet365 | |||||||
 #20Vanderbilt 3-043% u53½ -110BetMGM | |||||||
 #3LSU 3-0- u52½ -105Bet365 | |||||||
 #8Texas 2-136% u52 -111Caesars | |||||||
 Utah State 2-1- u61½ -110Bet365 | |||||||
 Texas State 2-1- u54½ -105FanDuel | |||||||
 UTEP 1-214% u47½ -109BetRivers | |||||||
 Colorado State 1-130% u59½ -110Bet365 | |||||||
 Colorado 1-243% u44½ -110Caesars | |||||||
 San Diego State 1-1100% u47½ -115BetMGM | |||||||
 #25USC 3-056% u56½ -115BetMGM | |||||||
 Hawaii 3-122% u47½ -105BetMGM | |||||||
 Charlotte 1-317 u42½ -110Caesars |
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