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The upcoming Saturday football game on November 15, 2025, features the Notre Dame Fighting Irish visiting the Pittsburgh Panthers at Acrisure Stadium in Pittsburgh, PA. This NCAAF regular season Week 12 matchup is set to be an exciting contest, broadcasted live on ABC and ESPN networks, giving fans plenty of opportunities to catch the action.
For bettors, understanding the injury report is crucial before placing wagers. Notre Dame is dealing with several injury concerns including key players like Gabriel Rubio (Defensive Line) who is questionable with a left elbow injury expected to return by November 8. Tight End Cooper Flanagan is also questionable due to Achilles surgery but might be back for the game day. Wide Receiver Jaden Greathouse is out with a hamstring injury, impacting the Irish's offensive options. Offensive Line players Charles Jagusah and Billy Schrauth have injury questions and absences that could affect the team’s line performance. Running Back Dylan Devezin and Kedren Young are out for the season, which could weaken the ground game.
On the Pittsburgh Panthers side, multiple players are listed as questionable including linebackers Jayden Bonsu and Rasheem Biles, plus several offensive linemen and defensive players. Running Back Derrick Davis is out for the season, which may limit Pittsburgh’s rushing attack.
These injury statuses can heavily influence the game's dynamics and betting lines. Bettors should keep an eye on the final injury updates and player statuses before making their bets. For comprehensive details, you can check the latest NCAAF injury list. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
#20Louisville 7-229% -1½ -115BetMGM | |||||||
![]() #8Oregon 8-134% -24½ -115BetMGM | |||||||
![]() Connecticut 7-322% -7½ -105FanDuel | |||||||
![]() Charlotte 1-8100% +18½ -110FanDuel | |||||||
![]() #25Cincinnati 7-218% -6 -110Bet365 | |||||||
Navy 7-223% +10½ -114BetRivers | |||||||
![]() #2Indiana 10-016% -29 -112Caesars | |||||||
![]() #22Pittsburgh 7-270% +12½ -110Caesars | |||||||
Ball State 4-585% +2½ -106Caesars | |||||||
Oklahoma State 1-875% +20 -117SugarHouse | |||||||
#3Texas A&M 9-072% -17½ -110FanDuel | |||||||
![]() Northwestern 5-445% +11½ -115BetMGM | |||||||
LSU 5-417% -5 -110Caesars | |||||||
![]() Tulsa 2-740% +2½ -106FanDuel | |||||||
![]() Arizona State 6-38% -11 -114SugarHouse | |||||||
Kentucky 4-5- -21½ -110Bet365 | |||||||
Georgia State 1-876% +8 -112BetRivers | |||||||
UAB 3-678% +18½ -115FanDuel | |||||||
![]() New Mexico 6-317% -14 -115BetRivers | |||||||
![]() Missouri State 6-30% -4½ -105FanDuel | |||||||
![]() James Madison 8-170% -21 -109Caesars | |||||||
![]() Boston College 1-949% +17 -117SugarHouse | |||||||
![]() Duke 5-449% -4½ -110Caesars | |||||||
![]() #15Miami (FL) 7-26% -14½ -113BetRivers | |||||||
Michigan State 3-677% +7½ -114FanDuel | |||||||
#4Alabama 8-112% -5½ -113BetRivers | |||||||
Southern Miss 7-237% -3 -110BetMGM | |||||||
![]() #6Texas Tech 9-187% -23½ -110BetMGM | |||||||
![]() Louisiana-Monroe 3-667% +4½ -105FanDuel | |||||||
Illinois 6-310% -15 -113BetRivers | |||||||
#17USC 7-224% -6 -117SugarHouse | |||||||
![]() Western Kentucky 7-20% -13 -121SugarHouse | |||||||
![]() Nevada 1-892% +9½ +102Caesars | |||||||
East Carolina 6-373% -2½ -120BetRivers | |||||||
Tulane 7-20% -17½ -110Caesars | |||||||
#23Tennessee 6-31% -39½ -110BetMGM | |||||||
![]() Wake Forest 6-342% -5½ -115BetRivers | |||||||
![]() Florida International 4-575% +3 -118BetRivers | |||||||
![]() Georgia Southern 4-540% -3 -114Caesars | |||||||
![]() Sam Houston State 1-885% +10½ -118SugarHouse | |||||||
Baylor 5-482% +9 -114BetRivers | |||||||
![]() #7Ole Miss 9-118% -11½ -105BetMGM | |||||||
![]() Washington 6-38% -16½ -110Bet365 | |||||||
UNLV 7-212% -6 -110Bet365 | |||||||
![]() #5Georgia 8-168% -6 -110Bet365 | |||||||
Florida State 4-515% -13½ -115BetRivers | |||||||
![]() #1Ohio State 9-035% -31½ -105Bet365 | |||||||
![]() Missouri 6-327% -6½ -118FanDuel | |||||||
![]() Jacksonville State 6-375% +3½ -118FanDuel | |||||||
![]() Washington State 4-58% -7½ -115Bet365 | |||||||
#12Brigham Young 8-111% -3 -122BetRivers | |||||||
![]() Fresno State 6-329% -3½ -105BetMGM | |||||||
San Diego State 7-237% -1½ -112FanDuel | |||||||
![]() Akron 4-735 -7 -118SugarHouse | |||||||
![]() Western Michigan 6-417 +2 -139SugarHouse | |||||||
![]() Massachusetts 0-103 +10 -110BetMGM | |||||||
Miami (OH) 5-53 +5½ -105Bet365 | |||||||
Central Michigan 6-438 -2½ -110BetMGM | |||||||
![]() Old Dominion 7-333 -9 -115BetRivers |
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