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Nov 15, 2025 12:00 PM EST
Week 12
ND
-12½ (-110)o54½ (-110)
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Notre Dame Fighting Irish vs Pittsburgh Panthers Odds
Updated:Nov 14, 2025 2:18 AM EST
The upcoming clash on November 15, 2025, between the Notre Dame Fighting Irish and Pittsburgh Panthers at Acrisure Stadium in Pittsburgh, PA, promises an exciting chapter in the 2025-26 NCAAF season. This Saturday football event will be broadcast on ABC and ESPN networks, giving fans nationwide a prime viewing opportunity.
Currently, the point spread odds favor the Notre Dame Fighting Irish at -12½ -110, while the Pittsburgh Panthers are the underdogs at +12½ -110. Opening odds started at similar lines, indicating steady confidence in Notre Dame's advantage. Bettors should pay close attention to these betting lines, as they reflect the perceived strength and recent performance trends of both teams.
Notre Dame's dominant performance in previous matchups and Pittsburgh's resilience at home add layers of intrigue to this game. Watching how the odds shift closer to game day can provide valuable insights for making smart wagers. The over/under is set at 54 -110, suggesting a potentially high-scoring game, which bettors can leverage when considering totals bets.
For those looking to maximize their betting edge, exploring the latest NCAAF odds can be done easily via NCAAF odds page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
Spread (FULL GAME)
COVER PROB.EXPECTED VALUEBEST LINE
Notre DameSpread
-8.8%
EV
-8.8%
PittsburghSpread
+3.4%
EV
+3.4%
MONEYLINE (FULL GAME)
COVER PROB.EXPECTED VALUEBEST LINE
Notre DameMONEYLINE
-5.4%
EV
-5.4%
PittsburghMONEYLINE
+2.3%
EV
+2.3%
EXCLUSIVE BOOSTS
Notre Dame, South Florida & Michigan Each Cover -14.5 SpreadNotre Dame to cover -14.5 spread; South Florida to cover -14.5 spread; Michigan to cover -14.5 spread
Pittsburgh, Cincinnati, LSU & Arizona State All WinPittsburgh, Cincinnati, LSU & Arizona State to win
Boosts Available
Boosts are special bets with increased odds offered by sportsbooks for a limited time.
Total (FULL GAME)
COVER PROB.EXPECTED VALUEBEST LINE
OVERTotal
UNDERTotal
-12.3%
EV
-12.3%
Spread (1H)
BEST LINE
Notre DameSpread
PittsburghSpread
MONEYLINE (1H)
BEST LINE
Notre DameMONEYLINE
PittsburghMONEYLINE
Total (1H)
BEST LINE
OVERTotal
UNDERTotal
MONEYLINE (2H)
BEST LINE
Notre DameMONEYLINE
PittsburghMONEYLINE
Spread (1Q)
BEST LINE
Notre DameSpread
PittsburghSpread
MONEYLINE (1Q)
BEST LINE
Notre DameMONEYLINE
PittsburghMONEYLINE
Total (1Q)
BEST LINE
OVERTotal
UNDERTotal
Spread (2Q)
BEST LINE
Notre DameSpread
PittsburghSpread
MONEYLINE (2Q)
BEST LINE
Notre DameMONEYLINE
PittsburghMONEYLINE
Total (2Q)
BEST LINE
OVERTotal
UNDERTotal
Spread (3Q)
BEST LINE
Notre DameSpread
PittsburghSpread
MONEYLINE (3Q)
BEST LINE
Notre DameMONEYLINE
PittsburghMONEYLINE
Total (3Q)
BEST LINE
OVERTotal
UNDERTotal
Spread (4Q)
BEST LINE
Notre DameSpread
PittsburghSpread
MONEYLINE (4Q)
BEST LINE
Notre DameMONEYLINE
PittsburghMONEYLINE
Total (4Q)
BEST LINE
OVERTotal
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NCAAF Fri 11/14
 #20Louisville 7-229% -1½ -115BetMGM | |||||||
 #8Oregon 8-134% -24½ -115BetMGM | |||||||
 Connecticut 7-322% -7½ -105FanDuel | |||||||
 Charlotte 1-8100% +18½ -110FanDuel | |||||||
 #25Cincinnati 7-218% -6 -110Bet365 | |||||||
 Navy 7-223% +10½ -114BetRivers | |||||||
 #2Indiana 10-016% -29 -112Caesars | |||||||
 #22Pittsburgh 7-270% +12½ -110Caesars | |||||||
 Ball State 4-585% +2½ -106Caesars | |||||||
 Oklahoma State 1-875% +20 -117SugarHouse | |||||||
 #3Texas A&M 9-072% -17½ -110FanDuel | |||||||
 Northwestern 5-445% +11½ -115BetMGM | |||||||
 LSU 5-417% -5 -110Caesars | |||||||
 Tulsa 2-740% +2½ -106FanDuel | |||||||
 Arizona State 6-38% -11 -114SugarHouse | |||||||
 Kentucky 4-5- -21½ -110Bet365 | |||||||
 Georgia State 1-876% +8 -112BetRivers | |||||||
 UAB 3-678% +18½ -115FanDuel | |||||||
 New Mexico 6-317% -14 -115BetRivers | |||||||
 Missouri State 6-30% -4½ -105FanDuel | |||||||
 James Madison 8-170% -21 -109Caesars | |||||||
 Boston College 1-949% +17 -117SugarHouse | |||||||
 Duke 5-449% -4½ -110Caesars | |||||||
 #15Miami (FL) 7-26% -14½ -113BetRivers | |||||||
 Michigan State 3-677% +7½ -114FanDuel | |||||||
 #4Alabama 8-112% -5½ -113BetRivers | |||||||
 Southern Miss 7-237% -3 -110BetMGM | |||||||
 #6Texas Tech 9-187% -23½ -110BetMGM | |||||||
 Louisiana-Monroe 3-667% +4½ -105FanDuel | |||||||
 Illinois 6-310% -15 -113BetRivers | |||||||
 #17USC 7-224% -6 -117SugarHouse | |||||||
 Western Kentucky 7-20% -13 -121SugarHouse | |||||||
 Nevada 1-892% +9½ +102Caesars | |||||||
 East Carolina 6-373% -2½ -120BetRivers | |||||||
 Tulane 7-20% -17½ -110Caesars | |||||||
 #23Tennessee 6-31% -39½ -110BetMGM | |||||||
 Wake Forest 6-342% -5½ -115BetRivers | |||||||
 Florida International 4-575% +3 -118BetRivers | |||||||
 Georgia Southern 4-540% -3 -114Caesars | |||||||
 Sam Houston State 1-885% +10½ -118SugarHouse | |||||||
 Baylor 5-482% +9 -114BetRivers | |||||||
 #7Ole Miss 9-118% -11½ -105BetMGM | |||||||
 Washington 6-38% -16½ -110Bet365 | |||||||
 UNLV 7-212% -6 -110Bet365 | |||||||
 #5Georgia 8-168% -6 -110Bet365 | |||||||
 Florida State 4-515% -13½ -115BetRivers | |||||||
 #1Ohio State 9-035% -31½ -105Bet365 | |||||||
 Missouri 6-327% -6½ -118FanDuel | |||||||
 Jacksonville State 6-375% +3½ -118FanDuel | |||||||
 Washington State 4-58% -7½ -115Bet365 | |||||||
 #12Brigham Young 8-111% -3 -122BetRivers | |||||||
 Fresno State 6-329% -3½ -105BetMGM | |||||||
 San Diego State 7-237% -1½ -112FanDuel | |||||||
 Akron 4-735 -7 -118SugarHouse | |||||||
 Western Michigan 6-417 +2 -139SugarHouse | |||||||
 Massachusetts 0-103 +10 -110BetMGM | |||||||
 Miami (OH) 5-53 +5½ -105Bet365 | |||||||
 Central Michigan 6-438 -2½ -110BetMGM | |||||||
 Old Dominion 7-333 -9 -115BetRivers |
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