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The upcoming Saturday football clash on November 22, 2025, between the Syracuse Orange and Notre Dame Fighting Irish at Notre Dame Stadium in South Bend, IN, is set to be a thrilling NCAAF regular season game. This matchup promises intense action as both teams vie for a crucial Week 13 victory. Fans can catch the excitement live on NBC, making it a can't-miss event for college football enthusiasts.
For bettors, this game offers a great opportunity to capitalize on odds boosts and profit boosts available on various betting markets. An odds boost is a special wager offered at enhanced odds, providing a higher potential payout without additional risk. These boosted odds can apply to moneylines, spreads, parlays, or prop bets, making your bet more valuable.
Understanding the teams' performance and the venue's impact helps make smarter bets. Notre Dame Stadium's outdoor setting in South Bend might influence gameplay, and knowing this can guide your betting strategy. Keep an eye on the latest odds boost promos to maximize your returns on this exciting NCAAF event. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.
![]() #1Ohio State 10-031% -31 -115BetRivers | |||||||
Army 5-423% -9½ -118FanDuel | |||||||
![]() Wake Forest 7-333% -17½ -110Caesars | |||||||
Virginia Tech 3-725% +18 -109Caesars | |||||||
![]() #8Oklahoma 8-235% -5½ -110Bet365 | |||||||
SMU 7-354% -3½ -117SugarHouse | |||||||
![]() Iowa State 6-434% -3½ -105BetMGM | |||||||
![]() Northwestern 5-540% -3½ -110BetMGM | |||||||
#3Texas A&M 10-0- -54½ -110Bet365 | |||||||
![]() #4Georgia 9-163% -43½ -112Caesars | |||||||
![]() Georgia Southern 5-556% +11 -115SugarHouse | |||||||
![]() James Madison 9-149% -13½ -120FanDuel | |||||||
![]() Arizona 7-331% -6½ -114Caesars | |||||||
![]() Toledo 6-469% -27½ -110Bet365 | |||||||
Wyoming 4-626% -6½ -112Caesars | |||||||
![]() Kennesaw State 7-321% -6½ -105FanDuel | |||||||
Auburn 4-6- -27½ -110Bet365 | |||||||
#10Alabama 8-2- -50½ -107Caesars | |||||||
Appalachian State 4-673% +5½ -115Caesars | |||||||
![]() Florida Atlantic 4-684% +7½ -120FanDuel | |||||||
![]() UTEP 2-824% -3 -113Caesars | |||||||
![]() Middle Tennessee 1-950% -6½ -113BetRivers | |||||||
![]() Louisiana Tech 5-524% +1½ -115FanDuel | |||||||
UAB 3-773% +21½ -109Caesars | |||||||
![]() North Carolina 4-671% +7 -115BetMGM | |||||||
![]() #17Texas 7-313% -8 -115BetRivers | |||||||
![]() #7Oregon 9-160% -10 -110Bet365 | |||||||
Iowa 6-459% -16½ -110Bet365 | |||||||
![]() UTSA 5-567% +2½ -108Caesars | |||||||
![]() #14Vanderbilt 8-217% -8 -115SugarHouse | |||||||
![]() South Alabama 3-757% +1½ -115BetMGM | |||||||
![]() Florida International 5-560% -1 -115Bet365 | |||||||
#9Notre Dame 8-272% -35 -110Bet365 | |||||||
Temple 5-584% +9½ -105FanDuel | |||||||
UCF 4-623% -13 -110Bet365 | |||||||
Maryland 4-672% +14 -107Caesars | |||||||
![]() #23Houston 8-228% -1 -113BetRivers | |||||||
![]() #12Utah 8-269% -15½ -125BetMGM | |||||||
Troy 6-423% -9½ -118FanDuel | |||||||
![]() South Carolina 3-759% -23½ -122FanDuel | |||||||
![]() Clemson 5-5- -41½ -110Caesars | |||||||
Texas State 4-629% -19½ -110Bet365 | |||||||
![]() #16Georgia Tech 9-117% -2½ -110Bet365 | |||||||
![]() Penn State 4-634% -7½ -113BetRivers | |||||||
![]() Boise State 6-40% -16½ -110Bet365 | |||||||
Air Force 3-789% +4 -120SugarHouse | |||||||
Florida 3-788% +4½ -112BetRivers | |||||||
Stanford 3-781% +3½ -113Caesars | |||||||
![]() Wisconsin 3-757% +8½ -110BetMGM | |||||||
Rice 5-588% +18½ -112SugarHouse | |||||||
LSU 6-48% -21½ -110Bet365 | |||||||
![]() Cincinnati 7-338% +3 -113Caesars | |||||||
![]() Colorado 3-785% +7½ -115Bet365 | |||||||
UCLA 3-790% +10½ -110Bet365 | |||||||
San Diego State 8-211% -11½ -114FanDuel | |||||||
![]() Fresno State 7-317% -2½ -115Bet365 | |||||||
![]() Ohio 7-442 -33½ -115BetRivers | |||||||
Bowling Green 3-816 -2½ -110Bet365 | |||||||
![]() Northern Illinois 3-819 +7½ -122FanDuel | |||||||
Buffalo 5-620 +2½ -107Caesars | |||||||
![]() Kent State 4-716 +8½ -115FanDuel | |||||||
Arkansas State 5-630 -2½ -110Bet365 | |||||||
![]() North Carolina State 6-521 +7 -118SugarHouse | |||||||
UNLV 9-238 -2 -121SugarHouse |
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