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The upcoming Saturday football showdown on November 22, 2025, between the Southern Miss Golden Eagles and South Alabama Jaguars promises an exciting battle at Hancock Whitney Stadium in Mobile, AL. This NCAAF regular season Week 13 game is set to be broadcast on espn+, giving fans plenty of reasons to tune in.
Current odds favor the Southern Miss Golden Eagles as favorites with a point spread of -1 -110, while the South Alabama Jaguars hold the underdog position at +1 -122. Opening odds started more balanced, but the slight move toward Southern Miss indicates growing confidence in their edge. The total points line is set at 53 with an under at -110, reflecting expectations of a competitive yet moderately scoring game.
These betting lines and odds provide crucial insights for bettors looking to make smart wagers. The shift in the point spread suggests Southern Miss might have gained momentum or key advantages since the opening lines. Bettors should consider these dynamics alongside team form and venue factors when placing bets.
For those interested in exploring more NCAAF betting opportunities, check out the latest NCAAF odds. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook like Caesars and profit off the edge.
![]() #1Ohio State 10-031% -31 -115BetRivers | |||||||
Army 5-423% -9½ -118FanDuel | |||||||
![]() Wake Forest 7-333% -17½ -110Caesars | |||||||
Virginia Tech 3-725% +18 -109Caesars | |||||||
![]() #8Oklahoma 8-235% -5½ -110Bet365 | |||||||
SMU 7-354% -3½ -117SugarHouse | |||||||
![]() Iowa State 6-434% -3½ -105BetMGM | |||||||
![]() Northwestern 5-540% -3½ -110BetMGM | |||||||
#3Texas A&M 10-0- -54½ -110Bet365 | |||||||
![]() #4Georgia 9-163% -43½ -112Caesars | |||||||
![]() Georgia Southern 5-556% +11 -115SugarHouse | |||||||
![]() James Madison 9-149% -13½ -120FanDuel | |||||||
![]() Arizona 7-331% -6½ -114Caesars | |||||||
![]() Toledo 6-469% -27½ -110Bet365 | |||||||
Wyoming 4-626% -6½ -112Caesars | |||||||
![]() Kennesaw State 7-321% -6½ -105FanDuel | |||||||
Auburn 4-6- -27½ -110Bet365 | |||||||
#10Alabama 8-2- -50½ -107Caesars | |||||||
Appalachian State 4-673% +5½ -115Caesars | |||||||
![]() Florida Atlantic 4-684% +7½ -120FanDuel | |||||||
![]() UTEP 2-824% -3 -113Caesars | |||||||
![]() Middle Tennessee 1-950% -6½ -113BetRivers | |||||||
![]() Louisiana Tech 5-524% +1½ -115FanDuel | |||||||
UAB 3-773% +21½ -109Caesars | |||||||
![]() North Carolina 4-671% +7 -115BetMGM | |||||||
![]() #17Texas 7-313% -8 -115BetRivers | |||||||
![]() #7Oregon 9-160% -10 -110Bet365 | |||||||
Iowa 6-459% -16½ -110Bet365 | |||||||
![]() UTSA 5-567% +2½ -108Caesars | |||||||
![]() #14Vanderbilt 8-217% -8 -115SugarHouse | |||||||
![]() South Alabama 3-757% +1½ -115BetMGM | |||||||
![]() Florida International 5-560% -1 -115Bet365 | |||||||
#9Notre Dame 8-272% -35 -110Bet365 | |||||||
Temple 5-584% +9½ -105FanDuel | |||||||
UCF 4-623% -13 -110Bet365 | |||||||
Maryland 4-672% +14 -107Caesars | |||||||
![]() #23Houston 8-228% -1 -113BetRivers | |||||||
![]() #12Utah 8-269% -15½ -125BetMGM | |||||||
Troy 6-423% -9½ -118FanDuel | |||||||
![]() South Carolina 3-759% -23½ -122FanDuel | |||||||
![]() Clemson 5-5- -41½ -110Caesars | |||||||
Texas State 4-629% -19½ -110Bet365 | |||||||
![]() #16Georgia Tech 9-117% -2½ -110Bet365 | |||||||
![]() Penn State 4-634% -7½ -113BetRivers | |||||||
![]() Boise State 6-40% -16½ -110Bet365 | |||||||
Air Force 3-789% +4 -120SugarHouse | |||||||
Florida 3-788% +4½ -112BetRivers | |||||||
Stanford 3-781% +3½ -113Caesars | |||||||
![]() Wisconsin 3-757% +8½ -110BetMGM | |||||||
Rice 5-588% +18½ -115FanDuel | |||||||
LSU 6-48% -21½ -110Bet365 | |||||||
![]() Cincinnati 7-338% +3 -113Caesars | |||||||
![]() Colorado 3-785% +7½ -115Bet365 | |||||||
UCLA 3-787% +10½ -110Bet365 | |||||||
San Diego State 8-211% -11½ -114FanDuel | |||||||
![]() Fresno State 7-317% -2½ -115Bet365 | |||||||
![]() Ohio 7-442 -33½ -115BetRivers | |||||||
Bowling Green 3-816 -2½ -110Bet365 | |||||||
![]() Northern Illinois 3-819 +7½ -122FanDuel | |||||||
Buffalo 5-620 +2½ -107Caesars | |||||||
![]() Kent State 4-716 +8½ -115FanDuel | |||||||
Arkansas State 5-630 -2½ -110Bet365 | |||||||
![]() North Carolina State 6-521 +7 -118SugarHouse | |||||||
UNLV 9-238 -2 -121SugarHouse |
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