Vanderbilt Commodores vs Tennessee Volunteers Picks

The upcoming Saturday football game on November 29, 2025, between the Vanderbilt Commodores and Tennessee Volunteers at Neyland Stadium in Knoxville, TN, promises an exciting clash in the 2025-26 NCAAF season. This game will be broadcast on ESPN, giving fans and bettors a prime viewing opportunity. Our picks suggest a competitive matchup, with Tennessee Volunteers favored to cover the -2.5 spread and win with a predicted score of 35-30. Vanderbilt Commodores are expected to put up a strong fight, but Tennessee's recent performance and prediction model give them a slight edge.

Our prediction model has been profitable in recent games, notably with a 55% hit rate on the point spread market for Tennessee and a 66% hit rate on the 2-way moneyline market for the Volunteers. These stats indicate a strong expected value (EV) and hit rate that bettors can leverage to make smart betting decisions. Additionally, the under 64.5 total points market shows promising potential with a predicted total score around 65, aligning well with recent trends and providing further betting tips.

For those looking to capitalize on this game, our detailed picks and predictions can be found on the NCAAF picks page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge. This Tennessee Volunteers vs Vanderbilt Commodores game is a must-watch and a great opportunity for bettors to find value.