Columbia Lions vs Harvard Crimson Betting Trends

The upcoming Friday football game on November 7, 2025, between the Columbia Lions and Harvard Crimson in the 2025-26 NCAAF season promises compelling betting trends to watch. The game will be held at Robert K. Kraft Field at Lawrence A. Wien Stadium in Manhattan, NY, and broadcast on ESPN2 and ESPNU, drawing football fans and bettors alike.

Columbia Lions have struggled this season with a 1-6 straight-up record and 1-6 against the spread, while Harvard Crimson boasts an impressive 7-0 straight-up and 5-2 ATS record. Columbia's offense averages 290.3 total yards per game with 197.6 passing yards and 92.7 rushing yards, but their defense gives up 378 yards per game. Harvard's offense is more potent, averaging 468.9 total yards with 284.9 passing yards and 184 rushing yards. Defensively, Harvard limits opponents to just 256.3 total yards per game.

The starting quarterbacks are key here: Columbia's QB faces a tough Harvard pass rush and secondary, while Harvard's QB enjoys a favorable matchup against Columbia's pass defense. Columbia's run offense versus Harvard's run defense also leans to Harvard, suggesting a ground game challenge for the Lions. The spread and total points odds will be crucial for bettors; expect a spread favoring Harvard given their dominant form and home advantage. The total points line will reflect the offensive and defensive contrasts between these teams.

Last season's matchup on November 9, 2024, saw Harvard win 26-6 at Harvard Stadium, underscoring Harvard's edge in this rivalry. Bettors can leverage these betting trends and game insights to make informed wagers. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.