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FINAL
Sep 6, 2025 12:00 PM EDT
IOWA 13 vs ISU 16
Week 2
9-4
Iowa
13
FINAL
16
8-4
#14 Iowa State
ISU
-3 (-113)o43 (-110)
tvFOX
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Cyclones vs Hawkeyes: Betting Trends & Insights

Updated:Sep 6, 2025 5:58 AM EDT

Get ready for an exhilarating matchup as the Iowa State Cyclones take on the Iowa Hawkeyes on September 6, 2025, at Jack Trice Stadium in Ames, IA. This Saturday football showdown, broadcasted on FOX, promises to be a thrilling encounter in the NCAAF. The Cyclones, coming off a commanding 55-7 victory over the South Dakota Coyotes, are in top form and ready to extend their winning streak. Key player Brock Purdy, the Cyclones' starting quarterback, has been pivotal in their success, showcasing impressive passing stats.

On the other hand, the Iowa Hawkeyes, led by quarterback Spencer Petras, are looking to bounce back after a mixed preseason. Their recent 34-7 win against the University at Albany Great Danes demonstrates their potential. The Hawkeyes will rely on their robust defensive line to counter the Cyclones' offensive prowess, particularly focusing on pass defense against Purdy's aerial threats.

With the Cyclones favored at -3.5, and an over/under set at 43 points, bettors should consider the Cyclones' strong home record and their ability to cover the spread. For those looking to make informed bets, the Cyclones' offensive momentum and Hawkeyes' defensive resilience will be key factors to watch. Explore the odds and place your wager on this exciting game, or start your OddsTrader Turbo subscription for comprehensive betting insights.

In their last matchup on September 7, 2024, the Cyclones edged out a narrow victory, 20-19, against the Hawkeyes, making this rematch even more intriguing.

What are the betting trends for Iowa State vs Iowa?

ATS Records

Iowa

Iowa State

All
  • All
  • 1st half
  • 2nd half
  • 1st quarter
  • 2nd quarter
  • 3rd quarter
  • 4th quarter
9-3-1 (18th)Against the Spread5-6-1 (172nd)
9-4 (56th)Straight Up8-4 (75th)
-0.0Straight Up Units+1.9
6-7Over / Under4-8

TEAM MATCHUP

Iowa

Iowa State

OFF
DEF
OFF
DEF
29.3Points27.4
320.1Total Yards395.9
5.5Yards Per Play6
143.2Passing Yards221.4
13.8 - 22 (62.9%)Completions-Attempts17.5 - 28.9 (60.5%)
6.5Yards Per Passing Play7.7
7.4Sacks-Yards Lost12.1
176.9Rushing Yards174.5
38.8Attempts39.8
4.6Yards Per Rush4.4
17.51st Downs21.1
7.1Passing9.9
9.2Rushing9.5
1.2Penalties1.7
5.4 / 12.4 (43.5%)3rd Down5.4 / 13.5 (40.1%)
0.9 / 1.4 (66.7%)4th Down1.6 / 2.3 (67.9%)
3.5 / 3.8 (92%)Red Zone3.5 / 4.3 (80.8%)
3 (30.1)Penalties (Yards)4.6 (40)
0.6Interceptions0.8
0.3Fumbles Lost0.4
62.2Total Plays70.4
6.2Kickoffs5.4
1.7Returns0.9
43.1Yards15.8
25.5Yards Per Return17.3
3.4Punts3.6
1.7Returns1
46.8Yards17.8
27.7Yards Per Return17.8

Recent Results

Iowa

Iowa State

Game
Score
ATS
O/U
vs Albany
Aug 30, 2025
W
34-7
L
-40
U
48½
at Missouri
Dec 30, 2024
L
24-27
L
+1½
O
41
vs Nebraska
Nov 29, 2024
W
13-10
P
-3
U
41½
at Maryland
Nov 23, 2024
W
29-13
W
-4½
O
40½
at UCLA
Nov 8, 2024
L
17-20
L
-6½
U
45½
vs Wisconsin
Nov 2, 2024
W
42-10
W
-3
O
40½
vs Northwestern
Oct 26, 2024
W
40-14
W
-16½
O
38
at Michigan State
Oct 19, 2024
L
20-32
L
-6½
O
39½
vs Washington
Oct 12, 2024
W
40-16
W
-3
O
41½
at Ohio State
Oct 5, 2024
L
7-35
L
+17½
U
45½
Game
Score
ATS
O/U
vs South Dakota
Aug 30, 2025
W
55-7
W
-16½
O
47½
at Kansas State
Aug 23, 2025
W
24-21
W
+3
U
51½
at Miami (FL)
Dec 28, 2024
W
42-41
W
+5
O
62
at Arizona State
Dec 7, 2024
L
19-45
L
-1½
O
50½
vs Kansas State
Nov 30, 2024
W
29-21
W
-1½
U
51½
at Utah
Nov 23, 2024
W
31-28
L
-6½
O
42½
vs Cincinnati
Nov 16, 2024
W
34-17
W
-7
U
52½
at Kansas
Nov 9, 2024
L
36-45
L
-2½
O
52½
vs Texas Tech
Nov 2, 2024
L
22-23
L
-13½
U
55
vs UCF
Oct 19, 2024
W
38-35
L
-13½
O
49½
View Full Season Game Log

HEAD TO HEAD

Iowa

IOWA

Iowa State

ISU
Matchup
SU
ATS
O/U
Iowa State @ IowaSep 7, 2024
20-19
ISU
+3
ISU
36
O
Iowa @ Iowa StateSep 9, 2023
20-13
IOW
-3½
IOW
35
U
Iowa State @ IowaSep 10, 2022
10-7
ISU
+3½
ISU
38½
U
Iowa @ Iowa StateSep 11, 2021
27-17
IOW
+4
IOW
45
U
Iowa @ Iowa StateSep 14, 2019
18-17
IOW
+1
P
42½
U

Iowa

UPCOMING SCHEDULE

Iowa State

Matchup
Date
Time
vs Massachusetts
tvBTN, 610
Sep 13, 2025
19:30 EDT
at Rutgers
tvFOX
Sep 19, 2025
20:00 EDT
vs Indiana
tvPeacock
Sep 27, 2025
15:30 EDT
at Wisconsin
tv219, FOX Sports 1
Oct 11, 2025
19:00 EDT
vs Penn State
tvPeacock
Oct 18, 2025
19:00 EDT
Matchup
Date
Time
at Arkansas State
tvESPN2, 209
Sep 13, 2025
16:00 EDT
vs Arizona
tvESPN, 206
Sep 27, 2025
19:00 EDT
at Cincinnati
tvESPN2, 209
Oct 4, 2025
12:00 EDT
at Colorado
tvESPN, 206
Oct 11, 2025
15:30 EDT
vs Brigham Young
tvFOX
Oct 25, 2025
15:30 EDT
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