SMU Mustangs vs Louisville Cardinals Player Props

The upcoming clash on November 22, 2025, between the Louisville Cardinals and SMU Mustangs at Gerald J. Ford Stadium in Dallas, TX, is set to be a thrilling Saturday football event in the NCAAF league. This game offers excellent opportunities for bettors focusing on player props, with a particular emphasis on passing yards and rushing yards prop bets.

Louisville's passing offense will face a solid SMU pass defense, creating a dynamic battle that will impact player projections significantly. Meanwhile, SMU's rushing offense will test Louisville's run defense, influencing rushing yards prop bets. The pass protection of both teams versus the opposing pass rush will also play a crucial role in the game's outcome and player props performance.

Our analysis highlights a high-value prop bet with Miller Moss (Louisville) under 1.5 passing touchdowns, boasting a 78.3% hit rate and an EV of 17.7%. This prop bet has shown excellent results in our last 10 games, providing bettors with a reliable edge. Additionally, Yamir Knight (SMU) over 41.5 receiving yards presents a strong opportunity with a 64.1% hit rate and 10.6% EV. These insights can help bettors make informed decisions and capitalize on the pace of play expected in this matchup.

Broadcast live on ESPN2, this game promises exciting moments and profitable player props. For those looking to dive deeper into NCAAF player props, check out our comprehensive NCAAF player props page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook and profit off the edge.