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FINAL
Sep 27, 2025 3:30 PM EDT
LSU 19 vs MISS 24
Week 5
7-6
#13 LSU
19
FINAL
24
13-2
#4 Ole Miss
MISS
-2½ (-120)o57 (-123)
tvABC, ESPN Networks
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Ole Miss Rebels vs LSU Tigers Odds

Updated:Sep 27, 2025 7:02 AM EDT

Before the game day, anticipation is building for the showdown between the Ole Miss Rebels and LSU Tigers. Scheduled for September 27, 2025, at Vaught-Hemingway Stadium in Oxford, MS, this NCAAF clash promises an electrifying Saturday football experience. Fans can catch the game live on ABC and ESPN networks. The current odds show Ole Miss as the slight favorite at -1½ -110, while LSU stands at +1½ -110. The over/under is set at 57.5, offering plenty of betting lines for savvy punters. These odds hint at a tight contest, making it a perfect opportunity for bettors looking to capitalize on small margins. For those interested in deeper insights, check out our NCAAF odds page. Ready to bet smarter? Start your OddsTrader Turbo subscription now or place your bet with a U.S. regulated sportsbook to make the most of this thrilling matchup.

What are the odds for the Ole Miss Rebels vs LSU Tigers game?
Spread (FULL GAME)
EXPECTED VALUECOVER PROB.EXPECTED VALUEBEST LINE
team
LSUSpread
-8.4%
EV
-8.4%
46%
team
Ole MissSpread
+4.5%
EV
+4.5%
57%
MONEYLINE (FULL GAME)
EXPECTED VALUECOVER PROB.EXPECTED VALUEBEST LINE
team
LSUMONEYLINE
-12.4%
EV
-12.4%
35%
team
Ole MissMONEYLINE
+9.9%
EV
+9.9%
65%
Total (FULL GAME)
EXPECTED VALUECOVER PROB.EXPECTED VALUEBEST LINE
over
OVERTotal
+1.6%
EV
+1.6%
55%
under
UNDERTotal
-8.4%
EV
-8.4%
44%
Spread (1H)
BEST LINE
team
LSUSpread
team
Ole MissSpread
MONEYLINE (1H)
BEST LINE
team
LSUMONEYLINE
team
Ole MissMONEYLINE
Total (1H)
BEST LINE
over
OVERTotal
under
UNDERTotal
Spread (2H)
BEST LINE
team
LSUSpread
team
Ole MissSpread
MONEYLINE (2H)
BEST LINE
team
LSUMONEYLINE
team
Ole MissMONEYLINE
Total (2H)
BEST LINE
over
OVERTotal
under
UNDERTotal
Spread (1Q)
BEST LINE
team
LSUSpread
team
Ole MissSpread
MONEYLINE (1Q)
BEST LINE
team
LSUMONEYLINE
team
Ole MissMONEYLINE
Total (1Q)
BEST LINE
over
OVERTotal
under
UNDERTotal
Spread (2Q)
BEST LINE
team
LSUSpread
team
Ole MissSpread
MONEYLINE (2Q)
BEST LINE
team
LSUMONEYLINE
team
Ole MissMONEYLINE
Total (2Q)
BEST LINE
over
OVERTotal
under
UNDERTotal
Spread (3Q)
BEST LINE
team
LSUSpread
team
Ole MissSpread
MONEYLINE (3Q)
BEST LINE
team
LSUMONEYLINE
team
Ole MissMONEYLINE
Total (3Q)
BEST LINE
over
OVERTotal
under
UNDERTotal
Spread (4Q)
BEST LINE
team
LSUSpread
team
Ole MissSpread
MONEYLINE (4Q)
BEST LINE
team
LSUMONEYLINE
team
Ole MissMONEYLINE
Total (4Q)
BEST LINE
over
OVERTotal
under
UNDERTotal
The best odds available today for LSU is +3 -114 at Bookmaker and for Ole Miss -2½ -108 at Heritage. The total for the over/under line is o56 -141 at Bet105.
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