LSU Tigers Vs Ole Miss Rebels Picks

Before the big showdown on September 27, 2025, between the Louisiana State University Tigers and the Ole Miss Rebels at Vaught-Hemingway Stadium in Oxford, Mississippi, anticipation is building. As part of the NCAA Football season, this Saturday football game promises to be a thrilling encounter. The Rebels, playing at home, have a predicted edge with a 64.8% chance of winning, according to our models. The predicted score favors Ole Miss at 32 to LSU's 27. With a total predicted score of 59, our top pick is the Over 54.5 points. Historically, our predictions have been quite reliable, securing wins in 6 out of the last 10 games, especially in the American Total market with a solid EV. Catch all the action live on ABC and ESPN networks. For more insights, check out our detailed NCAAF picks page. Ready to make smarter bets? Start your OddsTrader Turbo subscription today to gain the edge.